ID Q16LB4_AEDAE Unreviewed; 1652 AA.
AC Q16LB4;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=AAEL012698-PA {ECO:0000313|EMBL:EAT35115.1};
DE Flags: Fragment;
GN ORFNames=AAEL012698 {ECO:0000313|EMBL:EAT35115.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT35115.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT35115.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT35115.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT35115.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT35115.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT35115.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT35115.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CH477911; EAT35115.1; -; Genomic_DNA.
DR RefSeq; XP_001662816.1; XM_001662766.1.
DR STRING; 7159.Q16LB4; -.
DR PaxDb; 7159-AAEL012698-PA; -.
DR VEuPathDB; VectorBase:AAEL012698; -.
DR eggNOG; KOG0059; Eukaryota.
DR HOGENOM; CLU_000604_19_1_1; -.
DR OMA; YAIYIND; -.
DR PhylomeDB; Q16LB4; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF250; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 3; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 884..905
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1055..1075
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1087..1116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1136..1158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1170..1188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1268..1287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 513..742
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1333..1563
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAT35115.1"
SQ SEQUENCE 1652 AA; 185596 MW; 1BBFC6AA06CD534E CRC64;
AMTSSWDKFQ LLLWKNWTIQ KRHYIQTIFE ILIPVLCCSM LILVRGLVDP EIIDHPTVFS
PLQANYLVIP EITTPPVIPK IAYSPKNEVL EALLQDAIDN HLRTHNKLAI EGYPSSRDLE
GLLIQQNYFV GVEFDDSLAT VTSLPKKVHF SLRFPAETRQ WRWLFGNWRT NLLVVPFSPG
IRNGNLTDGG SPNYYAEGFI PLQVAISAAI VAAHDPEIIT QDVQLRRIPY PPFYKDELLP
AMEQLLPLII LIAFFYTCIN TVKYITIEKE RQLKEAMKIM GLSNWLHWTA WFVRCLLLLL
ITISLVTLLM TVSLTTNTDQ AVLQYTDWSA LWVFLLAFAI ATICFCFMMS VFFNKANTAA
GIAGLMWFLL MMPYNITVRN YDDMDTGSKV GLCLLSNTAM SYGVLNIVRF EGNQAGLQWS
NMFTPSTMND GLSVGVIIIM LLVDALIYLG IALYSEQVMP GEFGVAKPWY FLFTSEFWKR
NKVGDAHGSQ NGLVKPMQSK FIEEDPPIEK AGVKIRHLRK VYDKKVAVDG LDLNMYEDQI
TVLLGHNGAG KTTTMSMLTG MFSPSSGTAL INGHDIRTDI EGVRRSLGLC PQHNVLFNEL
TVAEHVKFFA KLKGVRDGDV AAEVEKYVNL LELTDKMNAQ SRTLSGGMKR KLAVGVALCG
GSKVVLLDEP SSGMDPSARR ALWELLQKEK LGRTVLLSTH FMDEADVLGD RIAIMAEGQL
KAVGSPFFLK KTFGAGYRLI CVKKANCDKD RLLEILKGYI PEVEVETDIG SELTMVLRED
YVQKFKPMLE DLEDNMESCG ISSFGISLTT MEEVFLRSGT DSFEKESLEN GTVIHTASSE
CKKAKICSSV DALDNLHLLT GKHLLFNQIK AQFLKKSLVT IRSLITLSMQ ILIPIVFVLM
TYIIILNSSA NQDLPALDIK LESYTHSVTV VQDQQSDVSI IQAYSALFNS LSPNHQLIVT
KEDMNDFILN KSLETIATVN TRYWVGATLN TTSPTAWFNN KAFHSAPLSI NLLFNALLKS
TCQECDIQVT NKPLPFQLMT RFDQLETGAN SGFQLAFNTG FAMAFVAALY IMFYIRERTT
RSKLLQFVSG VNVALFWAIS FIWDYLVFVV VSLFYLASVA AIQQDGWSNF EQLSRVFLVL
LLFGFAVIPT TYLFSYLFDV PATGFVKMML LNILSGSVLF TAVTLLKFDG IDLQDVANVL
EWVFMVFPNF VLSHSLNNLN MVASTEDLCA KQCALIPMCT KELLCMLVPQ CCGQEIFTFD
EGGINRNLLF LVGIGIVSFG LIMFIEFRVF KRIFDRKVTV SDAGNDSELD SDVLEEKRRI
AAMSQSEINT YNLVLKDLSK YYKKFRAVNN LSVGIRHSEC FGLLGINGAG KTSTFKMMTG
DESISGGQAW VNGISLQTNM NRVHQQIGYC PQFDALLEDM TGRETLKMFA LLRGVKNAEL
NSVSLALAEE LNFLKHIDKK TRAYSGGNKR KLSTALALIG NPAVVYLDEP TTGMDPGAKR
QFWNVICKIR EAGKAIVLTS HSMEECEALC TRLVIMVNGE FKCLGSTQHL KNKFSEGFLL
TVKVKREPME NLRARVDWVK LFVDQKFSGA VLKEEYLDSL SFLIPRTDLR WSAMFGLMES
ARNELEIEDY ALGQTSLEQV FLYFTKYQRE DQ
//
