ID Q16LL8_AEDAE Unreviewed; 2421 AA.
AC Q16LL8;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE SubName: Full=AAEL012607-PA {ECO:0000313|EMBL:EAT35210.1};
GN ORFNames=AAEL012607 {ECO:0000313|EMBL:EAT35210.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT35210.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT35210.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT35210.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT35210.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT35210.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT35210.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT35210.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477901; EAT35210.1; -; Genomic_DNA.
DR RefSeq; XP_001656149.1; XM_001656099.1.
DR STRING; 7159.Q16LL8; -.
DR PaxDb; 7159-AAEL012607-PA; -.
DR VEuPathDB; VectorBase:AAEL021323; -.
DR eggNOG; KOG1473; Eukaryota.
DR eggNOG; KOG1632; Eukaryota.
DR OMA; CANEYEN; -.
DR PhylomeDB; Q16LL8; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd05509; Bromo_gcn5_like; 1.
DR CDD; cd15560; PHD2_3_BPTF; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00628; PHD; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 2181..2232
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2237..2288
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2315..2385
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 74..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1024..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1074..1138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1150..1174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1197..1246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1509..1529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1817..1852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1911..1987
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2027..2065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2107..2174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..749
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1038
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1074..1131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1157..1172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1197..1222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1830..1852
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1929..1947
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1964..1978
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2048..2063
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2115..2132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2133..2174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2421 AA; 271025 MW; 98034609206F6FA8 CRC64;
MIVTGRNTVK QFEYLLSKLD PVDLEMHLCK ELDERRDEII KHMTLTETIT SQQKGNKKSY
FELDNQRLEK LMEEEGLATK DADEKMDVDD QKGAGDSEAS NEKSNDEPNG DESSSKEDDD
SKASGDKHVT RLKTGSLTPR TFSSDEMKRK SSLTKEDEES RLTRNKLTQI SNGTLHFKLG
MENGFKAYVN QYSINPIALN KPQRNEDRDK KRHLSHKFSL TQASEFKWLG GGMNSTQTQI
ISTIKQSIIA LEQAVASPFL HQNWSKLRKT WIGAISACTK AKDFARILCI LQACMRSVIF
ASVWHEQLGH TKMYKITSAE REEKKKLEKR EKRERDDEEE RNRSTFNFVK YSLGLRHQVW
KQKGEEYRIH GQWDWVWMSY SRRKGKKPSR ETNEVSHVLI PIVAEVHKKL LKLDSKTHKA
YQLVRAGSTD LDFMTGNEAL DSRLEEKFNQ TETFQVPETF DVIDVSKALS TPGGRILYPK
IAKTASVLDG LLQRRVDLKE AEERKIAKVK DEEDISVNVI HKPETVQARL GECVEKQLQS
IINSRHNVNV RNSLPLNKQP INRSNGEQVE PLIEKILPLR SKYQDVNAVV QTNKCYSLDC
ENGLCYSPLC LQKQAIKDEL LPLLKKVQAL QSTPMANPTI AGVKSILEQK LTEYKAENFD
SMLANFSMNR YRSILDEWDS AHMHLIEYDE QLIQSMAAPK MPEEHNNNVT NEVEIKTEDA
PDMVVKEEIV STEGEPDLNG SERMDDSLKL NENSNSISEN SCDEPRSTRR GRPRSSKNNS
MVIEDTEVKV KEEEVMFLPK KEHKPNRRFA LPSRCVKKED SEDKELAPDG STRVYSVSST
KGKIYLRKAL EPEVKVKSET KPTAAVVGPV KPKYPAVNYF WTRKQTTSMM VLPMHELLKL
ARNGGRLSAA GFHHMAKNNN SVWPYPCARP LFKTCWLYRT LNLSTLSAVG LQLRIIWTCL
RWDDMAMKPA TSDGKHQVTT ESEIMSLEIL KHRFAGIFHE RMQYLRRKVV IPLELPKTVR
EVQSIRSGLR KRKRAESPQQ TEPQVSEEWI DEDKLELWEI KLYGEKQEKL AAAQAQHVTR
TSTGKLPISR QTPSTSGESS NSSTSTTSGN SGNNASTTNV QNKSAVISSK ASREEITEKM
EQQLRIQRAA HNQKRAMELK QQGQSADGAT PPKQTIVQRR IIVKNADGTT KVIQQNITQP
ARASPASATT AATSSPQAQQ ASPAPAKPDG PQKVQIIRGP DGKVSVRGLN PGQQLIQTAD
GKLHVLSAAP ATSVTVTSPT AVTQPQPQQI QVQPQQVQIQ PQQQAAPVVV SSPTVTQQIV
NKSPSIVVRN QAGQPIKQII QKQVVQKVSL RNCGQLIATT GSPVQKVVTQ SNLQQLLQGA
GQKVVVESNT GQSPVQTQKV LVATSPPGQP VQKQILIQNA TPGSPQQIII NQAGGQKVVQ
QIVASPGQQI MIGGQRIMIG GGQKIISNQP IQIQQNQQIQ QIQQIQQVQQ KVQQVHQIVT
STPQPQQPQQ IQIQIQQPVA QPPPQPQLQT IQAQPAPLTQ GQSLTQQLSS GKLQLANLNG
QQVLIRPLGN NQAQVVAHIK TQPNGTAQII PLANAVDPPP APVQPQTIQQ VVQAAPTQQA
TIQQVVQQPV TQTTIVQQAF NTSGGSQTTF QQLAAATQQQ QLQQQQQQQQ LDPVEQTLLQ
GQPPGTVIKC VTAQVIQTQQ GPRIVLQGLQ GSEFTPQQSA LVQQQVKQQL LKAQESNGKQ
GVLGPTKIYL AIQPSQQQVV AAQPPPLAPV QIKHDGGTTH IQLHQQVLAS NLNKQNVIRI
QPQQVSSPQP LPMQVEEQVL EQPSEPLAGE AKPAKEENAS DEDAKTSEEK DDSFVVTPDY
IQQTIKNALK QENLNPEIEE KLLNLQRYQE KQMKTDDRSA AIALQHNYSN MSSNREHHHH
HSTPVKSKKR SHRGEDDDDE WMMDTPKRRP TKSGGSSLSS VERKVHHVAS KDGDAPGSTK
KRTISQSDAS SASVAASAAA AAAAVLASVS AECAAAKEMA IPLEITTTTP VPNARSEAAR
KSNERRKQQQ ALLQQQQRQN KLQAQLNRHK EQLKKDILKK RSHLERELQV QIQKELSAEL
AARCKQEQQQ IKQEHSGKQH ATAAATPSTP AEKGSHTKKR SSASVSKEDK VQKTPKHAQG
SSKAEKASKA SGKKGSKKKE KILCLCRTPY DDTKFYVGCD LCHNWFHGDC VGISEEQSKE
IDEFVCSECK HARETQELYC LCKQPYDESQ FYICCDKCQD WFHGRCVGIL QSEAEFIDEY
ICPNCQINNS VNFANMKSLS AKEFDNLKKL IKQIQHHKSA WPFMEPVDPD EAPDYYRVIK
EPMDLQKVEN KVNNQTYHTL SEFIGDMTKI FDNCRYYNPK ESQFYRCAES LESFFVQKIK
FFRENLVEKK SAGTSSTSTS V
//
