ID Q16RM6_AEDAE Unreviewed; 521 AA.
AC Q16RM6;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN Name=5574064 {ECO:0000313|EnsemblMetazoa:AAEL010900-PA};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL010900-PA, ECO:0000313|Proteomes:UP000008820};
RN [1] {ECO:0000313|EnsemblMetazoa:AAEL010900-PA, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL010900-PA,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AAEL010900-PA}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL010900-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR RefSeq; XP_001661138.1; XM_001661088.1.
DR AlphaFoldDB; Q16RM6; -.
DR SMR; Q16RM6; -.
DR STRING; 7159.Q16RM6; -.
DR PaxDb; 7159-AAEL010900-PA; -.
DR EnsemblMetazoa; AAEL010900-RA; AAEL010900-PA; AAEL010900.
DR VEuPathDB; VectorBase:AAEL010900; -.
DR eggNOG; KOG0166; Eukaryota.
DR HOGENOM; CLU_018084_6_0_1; -.
DR InParanoid; Q16RM6; -.
DR OMA; EMIQMLY; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000008820; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 8.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
SQ SEQUENCE 521 AA; 57769 MW; 4D21918F86D0B718 CRC64;
MSNNAAHRHR YKNVGLDSTE MRRRREEEGI QLRKQKREQQ LIKRRNVNAA EELDQDAILA
DEPQTTDTHP LIKPETMLAL YSENVQDQLA ATQKFRKLLS KEPNPPIDLV IQHNIVPRFV
EFLANTSNST LQFEAAWALT NIASGTSEQT SVVIGAGAVP IFIKLLESPH IDVQEQAVWA
LGNIAGDSPE CRNFVLDAGV LEPLLLVLNS STRLNLTRNA VWALSNLCRG KNPPPDFSKV
EKGLPILARL MFHSDVEVLG DAVWAVSYLS DGPNDNIQAV IEAGCCRRLV ELLLHNNNNV
VSAALRAVGN IVTGNDTQTQ LILNCNALPC ILQLLSSPKE TIRKEACWTI SNIAAGNRQQ
IQAVIDANIF PSIIDLLSKA DFKTRKEAAW AITNATSGGT VDQIKYLVQA GCVPPMCELL
TVMDPKIVTV ALNGLENILK AGNQHKVKPN PYAVLIEECY GLDKIEFLQS HQNTEIYEKT
FNIIRTYFSN DEEDVAVAPS TENNQFQFNA DQSVPMDGFQ F
//
