ID Q177Q7_AEDAE Unreviewed; 646 AA.
AC Q177Q7;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=AAEL006062-PA {ECO:0000313|EMBL:EAT42407.1};
DE Flags: Fragment;
GN ORFNames=AAEL006062 {ECO:0000313|EMBL:EAT42407.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT42407.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT42407.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT42407.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT42407.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT42407.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT42407.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT42407.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477372; EAT42407.1; -; Genomic_DNA.
DR RefSeq; XP_001651789.1; XM_001651739.1.
DR AlphaFoldDB; Q177Q7; -.
DR STRING; 7159.Q177Q7; -.
DR PaxDb; 7159-AAEL006062-PA; -.
DR VEuPathDB; VectorBase:AAEL006062; -.
DR eggNOG; KOG4172; Eukaryota.
DR eggNOG; KOG4625; Eukaryota.
DR HOGENOM; CLU_013230_0_0_1; -.
DR OMA; CKICMSA; -.
DR PhylomeDB; Q177Q7; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR CDD; cd16647; mRING-HC-C3HC5_NEU1; 1.
DR Gene3D; 2.60.120.920; -; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR037962; Neuralized.
DR InterPro; IPR006573; NHR_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12429; NEURALIZED; 1.
DR PANTHER; PTHR12429:SF6; PROTEIN NEURALIZED; 1.
DR Pfam; PF07177; Neuralized; 2.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00588; NEUZ; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51065; NHR; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 32..186
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 269..424
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 593..634
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 194..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAT42407.1"
SQ SEQUENCE 646 AA; 70639 MW; AF8B978C8D3489CE CRC64;
KNKMKVLKKI KKRMGLAPRS ASSCPGPNNL PPLKFHYVHG DNIRISRDAS VARRYESFCK
GITFSARPVR VNERVCVKFL DISNNWSGVI RFGFTCNDPA TLRGNLPKYA CPDLTNKPGF
WAKALNELYC YRNNVLFYYV TASGDVHFGI NGEEKGVFIT DVDSRGPLWA VIDVYGNSTA
IEFLDSRIYM FQQQQHHQHH HHNHNQQQPA PSQSCGRRSA DQEIVPQLES LSINQHNQQL
LEERPVPTTA VVSSAASMRY NSPAPGLLPL PFHPIRGRNI KFSPDRTIAT RAETEFCQGY
VFAPHPIKIG ERLIIQILKT DTMFVGSLAL GLTSCDPATL QLSDLPDDSD LLLDRPEYWV
VSKDVASTLV RGDELCFSIS VKGEVTISKN GGAPSVIMHI DQSLQMWAFL DVYGSTQSVR
LFRHAIPTPV ATASCSALYP EHRSMTASAS QRSLQVQPTS QQAHPTTTAT IRPDMIQINP
GGTVLVVNLP PTDVISPASS QPSVQQAQAT IVSRGLPSSA STLSVPLSTL SLSSHSGSTG
TGDHVPAYSY AEVRISASTS SLSGPSSSCS STPLPTPSMG VNPPIYSSTG VDCTICFEKP
IDSVLYMCGH MCMCYDCAIK QWRGIGGGHC PLCRAVIRDV IRTYKS
//
