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Database: UniProt
Entry: Q179M4_AEDAE
LinkDB: Q179M4_AEDAE
Original site: Q179M4_AEDAE 
ID   Q179M4_AEDAE            Unreviewed;       776 AA.
AC   Q179M4;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   22-NOV-2017, entry version 71.
DE   SubName: Full=AAEL005575-PA {ECO:0000313|EMBL:EAT42935.1};
DE   SubName: Full=Transient receptor potential channel 4 {ECO:0000313|VectorBase:AAEL005575-PA};
GN   Name=5566698 {ECO:0000313|VectorBase:AAEL005575-PA};
GN   ORFNames=AAEL005575 {ECO:0000313|EMBL:EAT42935.1};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT42935.1, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EMBL:EAT42935.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT42935.1};
RA   Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA   Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA   Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G.,
RA   Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M.;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EAT42935.1, ECO:0000313|Proteomes:UP000008820, ECO:0000313|VectorBase:AAEL005575-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT42935.1}, and Liverpool/LVPib12
RC   {ECO:0000313|Proteomes:UP000008820,
RC   ECO:0000313|VectorBase:AAEL005575-PA};
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
RA   DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
RA   White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
RA   Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
RA   Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
RN   [3] {ECO:0000313|EMBL:EAT42935.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Liverpool {ECO:0000313|EMBL:EAT42935.1};
RG   VectorBase;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|VectorBase:AAEL005575-PA}
RP   IDENTIFICATION.
RC   STRAIN=Liverpool/LVPib12 {ECO:0000313|VectorBase:AAEL005575-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; CH477348; EAT42935.1; -; Genomic_DNA.
DR   RefSeq; XP_001651106.1; XM_001651056.1.
DR   ProteinModelPortal; Q179M4; -.
DR   STRING; 7159.AAEL005575-PA; -.
DR   EnsemblMetazoa; AAEL005575-RA; AAEL005575-PA; AAEL005575.
DR   GeneID; 5566698; -.
DR   KEGG; aag:AaeL_AAEL005575; -.
DR   VectorBase; AAEL005575-RA; AAEL005575-PA; AAEL005575.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   InParanoid; Q179M4; -.
DR   OrthoDB; EOG091G0JDU; -.
DR   PhylomeDB; Q179M4; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008820};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      9     31       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     70     88       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     95    120       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    131       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   776 AA;  85420 MW;  1C34DEF56DDDBE60 CRC64;
     MVIDIVKFFF IYSLVLFAFA CGLNQLLWYF ADLEKSKCYS LKGGLPDWDN QGDACMKWRR
     FGNLFESSQS LFWASFGMVG LESFELAGIK SYTRFWGLLM FGSYCVINVI VLLNLLIAMM
     SNSYAMIDEH SDTEWKFART RLWMSYFEES STLPPPFNIF PNMKHVMRLC GKKKKRDIKR
     ESTIRRKEDK ERAERYTNVM RSLVWRYVSA MHRKMEENAV TEDDINEVKG EISAMRYELL
     EIFEKNGMDV SAADRKEKAV LAKRMKIWER RLMKDFHVAP VDMQDNALEE EDEEEDANPL
     ARFRRVARKV ATQTTSAKWG QVMSGVGIET NSQIGRCKNR DSFRQQQQLQ KAMNEARRLV
     ERSPLPRSRS ASPMMDGYED ETTNTLLQLI NQLAEETGGD VSPGNTLHAS GKHSRSTTPL
     NMLTAQLQTM LSKTPSPMPM KSLKTGDART PGNLSRSPAP RMEGKTPLAS ISGSKPTSPE
     PSAPVETKTN LGVRSPPTIK SPPPMKSPIQ PVQSPPPMIR ITSTESQLIK KSESNDSLVD
     AAPTVEIKPP TPQPSKPSSP VLPKSDAPGQ PEPVKKVEEK PGETVVHADD PSPLVAGVNS
     PPKVIKRKAP TPSAPDAAAA GDIAVSRPIA AKPQPGQGML PPPPSKEEQT PAPSNISIPV
     LSTTPATPLP ATKNLGATPK QPSPASVPPP IAPKPQSPPP VPPKVTSPPP TVKVETMAEQ
     QQQSEVTSST EKLIGSSSGD PSADAARAAS SPTCLRPINK IADVKTIKRQ PKSGWL
//
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