ID Q17B72_AEDAE Unreviewed; 2259 AA.
AC Q17B72;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=AAEL005066-PA {ECO:0000313|EMBL:EAT43495.1};
DE Flags: Fragment;
GN ORFNames=AAEL005066 {ECO:0000313|EMBL:EAT43495.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT43495.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT43495.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT43495.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT43495.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT43495.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT43495.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT43495.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477325; EAT43495.1; -; Genomic_DNA.
DR RefSeq; XP_001650305.1; XM_001650255.1.
DR STRING; 7159.Q17B72; -.
DR PaxDb; 7159-AAEL005066-PA; -.
DR VEuPathDB; VectorBase:AAEL024980; -.
DR eggNOG; KOG1786; Eukaryota.
DR HOGENOM; CLU_000276_0_0_1; -.
DR OMA; THDRLHF; -.
DR PhylomeDB; Q17B72; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF163; LYSOSOMAL-TRAFFICKING REGULATOR; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 1439..1530
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 1533..1831
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2030..2071
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAT43495.1"
SQ SEQUENCE 2259 AA; 258452 MW; 2322F973CFCA0DC3 CRC64;
VNQHICNIVV DILVELSKKC ATDPQNWCST LSQMVLKLNG IKNHLGGSLY LITGFGPVLQ
RSDVRLKELQ TSILELITDL DSPEVFSKFL QLLSLDDPPV QLILTKLMNL VDTTFKLESY
TEISFPDPSD DGTRISTCDV LLSKKISYLR EHHRFYNIRS PFTCSAKMIP LSYVNFSPWN
AEGCTASVWF RLSSTQQDSN RLTITHLISV GSEKQIVSVF INRQRQFTVR FNKPDRIISS
ANTKRYLASA LNVSCCDTCV KELSHMWSYK NFLRSIEPSV SCVYCYKHLP VGKTEASTSL
SNDYFYDLHS EQYTIKDLQL VEDQWTSLVL SVQQLDNSIS IVLTLDGVQQ QTLTIADPCQ
IHIDTALPVL ALGHRIGVED DCPINYSLSN VQLFRKSFTD ISTLANLYSL GPNWIHLAGF
LKGEIVPNYG SLNLTKLSLE DLHPRNHFHM LHRSHVGSYA AHKPDVFISG KPGYGRIALG
MLSFSPRIVP QENLSLQRSI QLSGGISAML FAFARVVELS DSPRIHADAL NLLLRIAHDN
NDFYNEFVQR DLLELVGIVL KNKKCHKEVC VLAAMLEVTF DQPILVYRGD SYSVLTNSVA
RIRYPEIIVF FFENFQIWID HSEEVLNLVF KVLMTITRDK HPGMDFNCKR LADAGLVPTL
IDFCRMNFVI PPKTVKISEA AADWLVALIK NLSSNPPKVS LLKEIIDLLL LMHKPTDSYV
THDRQKFYFN INPHLPNKST KTSENKLSQR LNLRERRLKY SQLRKIIPLA ISNTNNASFE
STTSFIEMGK LESKTIDSFE ASPQVTPRSL HGSPTAGNYQ ANYNKLNQAL AKVNIRRKSL
KSEKRKVLSF YGFGRLQNTN HFIPITEFFE QNYFGTGNDF IQESFLRAMC DLLLILPDQE
AKQFFSAENQ IIETLLILAN NSNIRIRTMI INLIAVISDR ILCSSYTEEQ FKIFWHHLGN
QIGSHSVSIE LLNSCFRWIT KTGSVLALES LILEYHVSVV QECGLNVLMA ILPQSHIDSR
LFQLVLHLMD YIGVKHPKAT QYMVDNGLVG TIVKTAVKMH EKDETGEVIA NRDSFLSFIT
NFAQRALISE NSINPFWDLI SGLTLAEGHK NPKVTQGIRD IQALFYRNLL QLFIYRPTDS
IIGHKNNYRL ILIEEAKARF NQIHDKAVQF ITNCDADHQV FEAEVLLIKS LMNRTLNGNP
RGGNIILWCL LPKRPASLKL YTIRQLGQYI DSGNYLSLIC DVRMLKVFSN SILLLNHKDL
SVEDLAFVNS FCKAIDGTHN IMWTLTQTIE EFDYLRKTNM NEQEQTIQKS INKQEKLIHT
CTIAAMEITR NIVEKQNKLR KELIIQLKKD NDFKFFNQWR QIIAQMTHED APWYNERLYP
TSWELDDTYG PGMVQNRMKR CHQTVEQRFL QKDFRTFDDQ PLKPLLDYLI PHNRSQEFSM
ENQVLYTWTV RQISPKEERD CECILTSTEL VLSLSTGDIS IYDLHDITKI WKKRYQHQET
AVEIFLQSDK SLFLVFDKSL EREQFVGFFH DLVQREGRQE LEVHTQAWKE GLLSNWEYLM
HLNQISGRSY HDLMQYPVFP WILADYESQT LDLLLEKTFR NLEKPIAVQY KDQEKHYINN
YNYLKQAESD LHSRQRIHPY HYSSHYSNSG TVLHFLVRML PFTSLFLQYQ DDSFDIPDRT
FHSLATTWKL ASKDSPTDVK ELIPEFYCCP EFLENAEGFD FGLRQSGEPV DHVELPSWCH
QSTRLFILIH RQALECDHVR RRISSWIDLI FGYKQTGSAA VDAINVFHPA TYANFNATDI
DDPVEKLALE TMVKTYGQMP RQLFDSPHPQ SNVTPLWANP PEVIDKVSGL KWGLYSGSPV
LPSPKIVDIR ATLNNLATLT HMEGNRVVGL PSRMNIFRGQ HTKAHYLMNW GHLDDVVRFR
SIQESDTRSS ELVYNTNMDP ITACGSDPNC PDIWFGHRSG RIAVFQQRQQ KKMSFFNANI
QPTVTRSRSS SFRKWIDRKS ATLRRKFEGD EEGEESTGGV PIKWNFPVIL IKHRAEITAI
AISTEFKIVV SVGVDGTAAI WDCNTLSYVR EIPKPVNGIN SKISLVAISP TLGDIVTVHS
STHAASLSSR SNDTTTLVDD ESFEVTENYN MDYVNVAMVS SRDQLRLHTI NAKYVEHVFM
ESPVMAVCYT SVKEGCGVNC IAVGMECGVI RLYSSWNLAL VREITTNLGD PFGIISLIYS
KNQHLVVLMS SNVIQTWKSE GLPGTSPQIS ELPVRRSIG
//
