ID Q17DN7_AEDAE Unreviewed; 1006 AA.
AC Q17DN7;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=AAEL004117-PA {ECO:0000313|EMBL:EAT44538.1};
DE Flags: Fragment;
GN ORFNames=AAEL004117 {ECO:0000313|EMBL:EAT44538.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT44538.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT44538.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44538.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT44538.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44538.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT44538.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44538.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH477292; EAT44538.1; -; Genomic_DNA.
DR RefSeq; XP_001648449.1; XM_001648399.1.
DR AlphaFoldDB; Q17DN7; -.
DR STRING; 7159.Q17DN7; -.
DR PaxDb; 7159-AAEL004117-PA; -.
DR VEuPathDB; VectorBase:AAEL004117; -.
DR VEuPathDB; VectorBase:AAEL013182; -.
DR eggNOG; KOG0920; Eukaryota.
DR OMA; XDYRHSE; -.
DR PhylomeDB; Q17DN7; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.10.590.10; ph1033 like domains; 1.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007275; YTH_domain.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF04146; YTH; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 30..198
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 254..426
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 839..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..877
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1006
FT /evidence="ECO:0000313|EMBL:EAT44538.1"
SQ SEQUENCE 1006 AA; 112949 MW; 141F7CD9DCB59333 CRC64;
KCIPPPTNSS MQIIQERLRL PIAPYRDAIM NCLAQNQVMI ISGSTGSGKT TQIPQFILES
ATQQGEACRI ICTQPRRLSA ITVADRVSYE RNEQLGQTIG YQIRLESRLS PITNLVFCTN
GVLLRCLMGK NSTSILNDVT HIIVDEVHER DQYSDFLLIS LKEKVLQHTN IKIILMSATI
ESNTFSRYFN NCPLIEIPGR LFPIESYFLE DVLYRIDRYN AKIDELQTPP RQLAKVLLDV
YHSTVNDEKI DHRLILDIIK YICTKLAPGA ILVFLPGYDD ILEQYETLNC GLSATTNFRI
YMLHSNMQTN DQNAVFKPVP PNTRKIILST NIAETSITID DVVYVIDSGK VKQKHYDSVT
STTSLTATWI SQACATQRAG RAGRTKPGVC FRLFTRQRFD AMDKFTLPEI LRVPLTEICL
QTSIIASHTS ILNFLSKAIQ PPSTMSIKQS IKLLQKLGAL DDDENLTELG LILADLPVDA
RLGKILLYGI FLKCIDPVLT IVSALSVNDP FVLPTTALDK DKAAKLKRDM AEDSYSDCLC
LLRAFQKWNE LKPSMKERQF CNRFFLNSGT MDTIGSLRSK ILGHLRSVGL VKSYGAGNIQ
DLNQNADNWA VVKACLVAGL YPNICRVDKE NATIKTRIDK KISPHPSSVI RDKSLKKNKE
SILSLPSEWI VFEEKTRAGI HCLIKCNTVV APVTIALFCG PLFLNEEEAL ISWRELDESN
SDYDEHDMSD KSKLIVDDWI NFAVDSYFGA SVFEFRNKLS ALFLKFISHP RSYQPSTNDL
YLLNTVAQLL KDEDRHLGFA GHSNIGQKPR PVIQNHLNVN GGAGNAFNFS ANDFKLAASS
NNSSSNNGNG SSGHNSNNKY HNRNQQQHGA GGKQHNNNNR KGDPKVRYFV VHAASSLQIE
LVAETPDAWS FTSSLQPKLL KILKKQPNLS IILFFHISQN KCFHGAGRLT LVANRTHLNL
FSKNTVSFET LSTFEKSFMR GRVLEEYLDG EELSPSSGHE LMEFFK
//
