ID Q17EB4_AEDAE Unreviewed; 1262 AA.
AC Q17EB4;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=AAEL003853-PA {ECO:0000313|EMBL:EAT44865.1};
GN ORFNames=AAEL003853 {ECO:0000313|EMBL:EAT44865.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT44865.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT44865.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44865.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT44865.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44865.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT44865.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT44865.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477283; EAT44865.1; -; Genomic_DNA.
DR RefSeq; XP_001657321.1; XM_001657271.1.
DR AlphaFoldDB; Q17EB4; -.
DR STRING; 7159.Q17EB4; -.
DR PaxDb; 7159-AAEL003853-PA; -.
DR VEuPathDB; VectorBase:AAEL003853; -.
DR eggNOG; KOG3515; Eukaryota.
DR HOGENOM; CLU_003881_1_1_1; -.
DR OMA; CEVSNIM; -.
DR PhylomeDB; Q17EB4; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45889:SF8; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 3.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 7.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00408; IGc2; 7.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 8.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 8.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 910..935
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..111
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 119..208
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 213..308
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 316..405
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 410..500
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 511..599
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 604..692
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 698..795
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 802..894
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 963..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1119..1196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..986
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1134..1160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1172..1187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1262 AA; 137632 MW; 7D8FDCAF624F6246 CRC64;
MLRDAPPSSI EIQGYENNSK VEVREGQDLT LTCVVANSKP VAQIVWRRGK SEVKSDSIEN
KVIETEGKRY TVTSQLRIKP GAADDYMGYT CQAKHKALHP EKPLQTTVQL SVLYPPGAPY
IDGYKQGETL RRGQSVELIC ASRGGNPPAQ LIWYKSGIQE RMAYRTSERL SENIYKFTAE
ASDNKAVLRC EANNIMAKAP LKTEVVLSVL FAPTHVTISG PSEARVGDRV PLQCQTAPSN
PPAEIKWSVG GHQVKNATSR TVESPEGGWI TMSNITAPVD ASKRSLVVIC HGLNMQLTEN
VVSTHTVNIL LPPSPPIISG YEEGQIIPAG SVQKLGCMST GGNPLATLTW YKNDKKVNSV
IKTADKSVSA ELTILANVTD NQARYRCEAH NSATEIPLFQ TKTLSVHFAP ETVKITIDPP
ELKPGIEATL ICDSSSSNPP AIISWWRDGI AVQGINNSSK AGLWGGTVSS LELKVNITQD
MNGNVYTCQS TNEALQRSVH EAVNLQVLYP PKFSPPPSST VVGFEGESLT VGMVANGNPM
SIAYTWTKEG LPIQTPGVQR IVSEGPILNI TKLTRNDAGV YTCEAVNSQG SAMINITIVV
EYGASIKSIS ENVVVNPGED AMLSCTVEGK PLNEEHIRWE RIGYDMTIKT STTYANGTSY
LHIKDARRED VGNFRCIADN RVANPTSRDV LLIVKFIPEI DKSPPMLRAA ASSGERGRLP
CRAQAAPRPK FYWSRAGQNL SVNQTSKYLV EYKHIDSLTY ESILLIERVS SNDYGVYECI
ARNELGSVKE SVRLDVTSPP DPPLSLNILN VTHDTVTVAW TPGFDGGMKA NYRVRYREAN
NDHYRYEDSL PNSHKLTITG LRMNTLYLFS VMASNALGSS KYLPDLTRAQ TKGPEPMPSE
LAEKAELPSF VIFCIALAGL CLLVVNAGLV AWFIIKKRSK DSSNQNSKSA TIEMYAPSSY
NDTVTGETLS SVSEKSDSYS NDGSQPDYMD ETRKKAASTY LVENSDMPPP RYQKDGTLPH
YPNNINAAHT RTLPHPRHNN VVYEQRSRDD QLIGKNNYVT APSPGPPMDG SYYNMNSDRY
LSYPPMDYPP MEFSTPPLPV IPALPTNNGT LRRGTRAMVP PPDVTHHTQH TVKTLHDSSA
SSGLLNISQV SQSTPKQPQG ILKDPNKRKD QQLQQQQHQQ SGLPPGAMNH LNSIGGGLQM
LGVQNPSPVP MMGGPPPGLV PVNAGGSSLG NNLLIGAYDP SSTNLSSFNA SLGYTDADGH
LV
//
