ID Q17F56_AEDAE Unreviewed; 1505 AA.
AC Q17F56;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=AAEL003575-PA {ECO:0000313|EMBL:EAT45127.1};
GN ORFNames=AAEL003575 {ECO:0000313|EMBL:EAT45127.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT45127.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT45127.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT45127.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT45127.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT45127.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT45127.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT45127.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; CH477276; EAT45127.1; -; Genomic_DNA.
DR RefSeq; XP_001663935.1; XM_001663885.1.
DR STRING; 7159.Q17F56; -.
DR PaxDb; 7159-AAEL003575-PA; -.
DR VEuPathDB; VectorBase:AAEL019878; -.
DR eggNOG; ENOG502RTIQ; Eukaryota.
DR HOGENOM; CLU_004212_0_0_1; -.
DR OMA; HYISSYN; -.
DR PhylomeDB; Q17F56; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF31; IRREGULAR CHIASM C-ROUGHEST PROTEIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 306..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..94
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 103..181
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 345..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 522..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1071..1107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1215..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1359..1468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1246..1267
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1369..1410
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1412..1426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1436..1468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1505 AA; 167925 MW; 8C831EA1F987A603 CRC64;
MYSRKLQKAK SILNAPTVRL LGAPQIDLEE GKDSLILRCQ ADANPTASIV WRRAGRSEIA
SLQESLQLRP VGRRDAGLYT CQAQNSVGTS ETLSVQLDVK YAPKILSAGP DRLTTAPLFS
PAAFECVAEG NPQPTYKWVQ RGRESRLVID NVTYDYQGEY ECRATNFING QERTATSDPI
ALQVVGAPQV LRSSSTASGH SVSVRKGDSA TLSLIVCADP RPRHVSWEWG SLRLEAGSGI
GRFRVDDVTQ DSREDCYLAT LHIDDADLQD QRPYYLVVEN DRGHDRHAVN LRVEGMFSVE
PLELSYLLGI AGGCLAAFLI LVCLCIYAIR TRKCCFRNRN NYKTSEKDSE KADLKSRSDS
TSVPPLDSIY TTPTGFHHHH HPNGTPGSPE AMKTDCTVKE SLADENENDG TNSRDSTSPK
NTPNADRSVP EGSDPTSRAD QTEPIVSVST SSQSQTTKSN NDSHIETNGG GIRLCKVTDY
SVEKFNRLLD KLDKGNILIK SNFKKSYSLI LTRSNVGERV SGGWNSTKES NNDSNNNCND
SIKGGGKMKK GNLIKANSSM GIYHQSAKSN EQREEQSDSK RKSPVMHDLN SIGDTGIQPD
MSGNGREMAI ERVNERRRLA DVGNNYNAKS LSLSYCNNEG SVDNNNDSDE FCRSEIFDND
STVPESQPDF VLNDLTGEKT VTGVHARKME NNYENIHPYS SSTLSHCSRK HIRRKSNISY
WNHHQENNNG QPSLSKTDHE AGSNNDARNK SAIPTRFFKR QDYAQPELDF PSDHSEVTGE
EKTFSKRGPK FATDLFQLPF GGSRKKHDKT APQLKNINLN FPNKTTYIDE QQLQQPQQPS
TKVVRQPHLV LQPTQWQKNE NKYFNKAKTQ ILKLGQRCKL IGSGKEKRNH YISSYNLDDL
IKATHKYEEN EKSNLSNKIV YKSYKSELDL TKNLAYLDTF LNETFDTNET SQQENARKVR
KPTRHGHKRA KSCSKTLDQM LMTASTTTAQ LPQRPNNART PQNLIVLDDD AWSSPQKKVS
ERQLKNNITP TASRSNKTKL ASLIKMENDF SATLVNGEDP FSDARLMMTG EKSGRSNTTS
SSLSSSDYAS VYSAPSSSGA GGNSSSATNK MQNLKLIGTP DEALLRSCGE RDVVIEHSTS
KRHPKARHEE YENNFSRSML LDDANSYYSL RANKSHHQIH NNFSDCSIPI EQRYHHQDQE
FHPHDFHNAS TLQLPRLAPN NPFRESSSQR QRATRDSAQQ QYRKQQNNPH HRRHQQHHRH
QHQRQWHHRK SPLEADLTYQ EDYLEHYQNT RAAAAASTAA SLGGCFNPTR SRGGSVASSA
GNIESNCDSS FEYFANQSYH YGNTIIDNDE TLRNNISVNE RGHSQRNDDD DDDDDNDVDG
EDDASNSPTD KDDEDDDEDG NEDDDNPNGD NDGDSGGKSV ISSNHGYGNH VAGRRSRAHS
FTNNISPNSD LLSSSRSFSR GTAKLSGGTI NPGFLSSYGP HRVIVSKAHK QHGSGGGELV
LEYEC
//
