ID Q17M37_AEDAE Unreviewed; 2386 AA.
AC Q17M37;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=AAEL001147-PA {ECO:0000313|EMBL:EAT47808.1};
GN ORFNames=AAEL001147 {ECO:0000313|EMBL:EAT47808.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT47808.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT47808.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT47808.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT47808.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT47808.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT47808.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT47808.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477208; EAT47808.1; -; Genomic_DNA.
DR RefSeq; XP_001652430.1; XM_001652380.1.
DR PaxDb; 7159-AAEL001147-PA; -.
DR VEuPathDB; VectorBase:AAEL019594; -.
DR eggNOG; KOG1844; Eukaryota.
DR HOGENOM; CLU_232897_0_0_1; -.
DR OMA; EYNCELC; -.
DR PhylomeDB; Q17M37; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR CDD; cd10529; SET_SETD5-like; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46462; UPSET, ISOFORM A; 1.
DR PANTHER; PTHR46462:SF3; UPSET, ISOFORM A; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
FT DOMAIN 459..588
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 640..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 920..953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 966..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1025..1053
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1065..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1363..1411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1452..1514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1722..1959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1971..2082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2237..2386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..703
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 999..1013
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1025..1050
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1089..1131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1138..1199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1200..1217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1218..1232
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1256..1270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1452..1477
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1722..1747
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1758..1789
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1790..1814
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1820..1876
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1883..1919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1941..1959
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1979..1998
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2049..2065
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2269..2331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2336..2351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2354..2376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2386 AA; 259456 MW; 3BA7EDA58326DF6F CRC64;
METLLKKRNV AFERLKREHA EEELPSVLNV REDYEKLFYI TEGMFTRILE VERPRGSYCG
SSDGTCIESD TGLKEAVRVL LETQRALLTR QAAASTTVEE LAGQFPHIVD IDNPTFEELL
KFLKRKCDTF ETCAAFSGKQ SDYVKKEIFK EERKNPAVKR EVSNFGVTQQ SCPICSSGDH
VIYQCATFKE ASVKERRDMA LQMRFATTVC VQTTAQNRVR QNLYTAHLIA SNDTILCCVS
PTKRNAWQHV DCMGIDRANI PDEYNCEMCQ PRPVDRIRAR TLQMEKRKEQ SLLLANNNLQ
IPVGDAAVTS TNLVGVVGTG PPTATVGTTA KGANQYTTGK ALAGTKKGKT TGSSKKKSSE
NAAAKKAAKK ALDALNRVNG KRKELKKPSK KKIKTTEQNA EKMSNMIRTW IDNYERAITN
HYSPELRARL TAFGKMQSQN PLLNSDRLIA PGSVINLAQK CTTVPHAGGK ILISIEEIPP
KTPIIEIRGK YMLSSQHKQL QSLFNMAANG KLSNNKNAGP FLFLYQVTQG GMELCVDTRT
YGNDARFVRR SCRPNAEILH NVEKGVVHLY VVSTANIKAN TEITIKHDEQ LIQRVGGVVI
LTHTTVTKLC ACGLIKDCQY SAQLSDGLLP AINPTGPNVP AIMPNVQGGV SSSTPSVPKA
TKSKKNNGAL GDGEKKLTKK RNSRSTSSNA EARLRSISSS GDSTSELMMY AQQQPPLSPL
QPNPQFQPTP SQLVHQQLQQ TAMHFMQQQQ QSQPGLMQPS QPVYMYSPSP THQSQPPALA
PTSSVQLQPP VIHPQTPPPH PPMSPVMNIA HRTTGFYTEI KSPMNSPPPL NLTGPPPLVI
PSMPSPIKTQ SQHPPPLQPM SDVVAPPPPP VAPPMDVPAL TISNHSHSSL QDHTRMDLIQ
QQQQIMEDII KIKIKSPKAS PYKHEYSPIP SSTTTATTSM LSPPPPPPIP VAQRPRCAET
LKQELFQSHY QPQVRSPSPA PPAISSPVKV EYTPPMEMKQ EPQPIPEPQP LVIDEKPPMA
MEIKTEEDIK PEPLPEPKLE VEEEKPLPVV KTEPEPVIEM EAVVKEEPAA VVVPPHEGDS
KDGIDTGASL CDSATNSPTK ASQLHQQQTP GANPGNSAHS SPHSTSSQHH PHGGSSKKKN
NPFKETETEK KEKPPSRKLT REERKMEAIV KAFEKMEQSQ QRKQELKEQR KEGKRRSVSS
STPDESIPSG SSSTKKKSLS SQKRKKKKSK SLSQHFGSPN QSRKKKVSKS SKKSKNARVL
ALDEETPARP YENKAAELLL TFSQSVKPVS KTFFGDDVKP LADVGSSNDN SVEPVSSASS
NLPLLSSACM LVEAAVGPLE QASSNSTVEQ DFKFPQKAKT KKSMSREWLS GQAVDAYRRN
TPDQDSGYMS EDKSHEYRRT PFEESSLTTP LGVDVSDPNI CIVAKKVEEF IAQNSPQPED
VAAAGYKWED KVSTSATSVN NSQEQTHTPT SGGNVSESAA AKKRWLRQAI SEETDELTQA
SSSPPPPNGF TTPLKKRRVI RQSDEVTIQP QPQQQQPTLL SAQKIDFADS LSAPQHQQQP
LVINSQQQFA ESSLQWSNSG PPPLTYPFGM SEDKQAIDLS RTGVPPVRLT TQQQRIQPYK
IVPIAQALTP LHFADPGPLP TPTTIPMSIP PVQAHHHLIP MEPREIVRQT PLPPLAVQHQ
ESVNHYERLP SPPPSAVAAM VPASLLPPEV TFVVPAEQQQ PQQARIDVSY PSSAPVPGIT
RSKGSQKYIG SPAKFEPPSP SESLSSSVAE TPEKNSVASS NSSGSLGNSD VDEDAHEEHP
SKPEVTEAVQ EEKVECPQAE MTMSTEQESV TATESSTTIT SSGSVSDVNS LEPSSQSETA
IIQEEQVITS EVVQEEQESS QMDESDTVMN STEEINVSQV EDVSEEQTAP SSASMEVDSE
DPSAKQPKAI IKTMNGREKG VPGAPEEDHD KNELEDLQKA IASFHSENIM NLISRNKKSK
KVVTRENSSD DKPRYAKKSA KNRSNASSKE GSVTPPAPPS PAPEEQEVSD PVVEPVIVDA
SSEVPVTCEP DPEPVPAPVP PPVEEPSLST LGRSYSHPSW HATDTFRDST EVRSYSTLRP
DIPQINYNSP STYQSKAARE LLSSLSAGSE PLSSFTSFRT STSSFLDYPK SSICGSATVT
SNSTTSNAFH YKASSEISSL LDKGFSSTRP SSFSTLGPDR STERVGSSYL LSSTKVTDNL
STLGSTSSAY PKIFTKTASS DPRLNPALTT PEPPASATPK RKLSINEYRQ RKMQSCSNTT
PSPSATSTVA TSTSATTAEA ASSSSSSSSS DSGGSNQISS SLGSNDVSSS ICKELELELE
LGEEKPSGDD AEAKAASSNE TSGSKGATTA KPEISANEAT GKTIVD
//
