ID Q17PE8_AEDAE Unreviewed; 1082 AA.
AC Q17PE8;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 24-JAN-2024, entry version 95.
DE SubName: Full=AAEL000345-PA {ECO:0000313|EMBL:EAT48672.1};
GN ORFNames=AAEL000345 {ECO:0000313|EMBL:EAT48672.1};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT48672.1, ECO:0000313|Proteomes:UP000682892};
RN [1] {ECO:0000313|EMBL:EAT48672.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT48672.1};
RA Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P.,
RA Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H.,
RA Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G., Utterback T.,
RA Rogers Y.-H., Kravitz S., Fraser C.M.;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAT48672.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT48672.1};
RX PubMed=17510324; DOI=10.1126/science.1138878;
RA Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL Science 316:1718-1723(2007).
RN [3] {ECO:0000313|EMBL:EAT48672.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:EAT48672.1};
RG VectorBase;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH477191; EAT48672.1; -; Genomic_DNA.
DR RefSeq; XP_001655564.1; XM_001655514.1.
DR AlphaFoldDB; Q17PE8; -.
DR PaxDb; 7159-AAEL000345-PA; -.
DR VEuPathDB; VectorBase:AAEL010445; -.
DR VEuPathDB; VectorBase:AAEL019826; -.
DR eggNOG; KOG3209; Eukaryota.
DR HOGENOM; CLU_004562_2_0_1; -.
DR OMA; NDHRITT; -.
DR PhylomeDB; Q17PE8; -.
DR Proteomes; UP000682892; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 3.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.42.10; -; 3.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR10316:SF40; LD27118P; 1.
DR PANTHER; PTHR10316; MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED; 1.
DR Pfam; PF00595; PDZ; 3.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00228; PDZ; 3.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50106; PDZ; 3.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
FT DOMAIN 161..194
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 208..241
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 307..377
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 485..561
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 954..1024
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 825..849
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 863..882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1052..1082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..118
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 825..845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..882
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..929
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1082 AA; 117236 MW; 92E8C7F51D5F6A20 CRC64;
MNDSMMPNGG GGGGNGSGST GVAAAGGAGS SSTISAKSET GKDLSKVGVN SSTMNGAGSA
GSGSGGTGRA SDNGSDTLGS EASTMMMMNP PPGGGGGPPH SHHHLHHIHH HHHGHNHHQQ
QQQQVPMGMT NGGGGGGGGG FYDQKSDISS TAQTEEDDGL GPLPPKWEKA YTDSGEVYFI
DHNTGTSHWL DPRLSKFQKK SLEDCQDDEL PYGWEKICDP HYGTYYIDHV NRKTQYENPV
LQAKRMTERG SAMSVGGHSS NGMNGSIGGG GGVGVGGVGH DEVGNGVGGR VNHFTKNPAN
LRGDRLMTTL VKSTRGLGFT IVGGDDNVEE FLQIKSIVPN GPAWIDGKLK TGDVLVYVND
ICVLGFTHHE MVNIFQSILP GEEVHLDVCR GYPLPFDPND PNTEVVTTIA VDGLNNGAMT
ESDLKFLETG GFMDSGDVQH KNPLAKIQSG SATANGGDVY FSDTHPYQQH YKSKENAFEI
PEILHINIVK SDNGFGFTIT DSSYGQKVKK ILDRQCCKNL QEGDVLLSIN SIPVKDMSHN
EVVQVLKDCP KNIETTLKVQ RGPSALLVGS SKMTNKLRKS IEMAKFGGGL LKKDGYGIGG
NSLFRSKTPT ADLYSTQAKE ILPTRPKTPL VDTRARAKTP SLPLSDLNTD EIELDVNKNT
GDHKMDLNLN LKSNSSSHDN DSIANDIGSF HNEDQFHSGK HPNLADRLGE LTISSSNNST
TDTIYHNHQP QYGPGSHLQH QQNFNGHGYN HLYSPPLVPP PPVPPLSANH AGYAPNPLPL
QPTYHHESCF CYDCQDYQRQ QQQLLHQQQQ QQQHQQMYQQ QTLNRSYGNN PSHLQQQQHP
YQLPPQMSDN IGKRLNEYLM DRKRSLHQQQ QQQQQQQHHQ PQYDNLYHHH KAPVPLPPQH
QQPPQQPPTQ FDQHFYPSQP GSWRSAPGQH SPQLYGGGAP FMAPVPMEEY SLTEVTLERQ
ALGFGFRIVG GTEEGSQVTV GHIVPGGAAD KDTRIASGDE ILNINGVNVT KRAVTLSGYA
MEGAGITWDN IGVEIYLDAL LADLQNTVPG HNQHVGGSSV PGYGSLNGAR NKQTPSPVKL
TL
//
