ID Q182G7_CLOD6 Unreviewed; 279 AA.
AC Q182G7;
DT 25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 25-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Hydrolase {ECO:0000313|EMBL:CAJ69367.1};
GN OrderedLocusNames=CD630_24800 {ECO:0000313|EMBL:CAJ69367.1};
OS Clostridioides difficile (strain 630) (Peptoclostridium difficile).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Clostridioides.
OX NCBI_TaxID=272563 {ECO:0000313|EMBL:CAJ69367.1, ECO:0000313|Proteomes:UP000001978};
RN [1] {ECO:0000313|EMBL:CAJ69367.1, ECO:0000313|Proteomes:UP000001978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=630 {ECO:0000313|EMBL:CAJ69367.1,
RC ECO:0000313|Proteomes:UP000001978};
RX PubMed=16804543; DOI=10.1038/ng1830;
RA Sebaihia M., Wren B.W., Mullany P., Fairweather N.F., Minton N.,
RA Stabler R., Thomson N.R., Roberts A.P., Cerdeno-Tarraga A.M., Wang H.,
RA Holden M.T.G., Wright A., Churcher C., Quail M.A., Baker S., Bason N.,
RA Brooks K., Chillingworth T., Cronin A., Davis P., Dowd L., Fraser A.,
RA Feltwell T., Hance Z., Holroyd S., Jagels K., Moule S., Mungall K.,
RA Price C., Rabbinowitsch R., Sharp S., Simmonds M., Steven K., Unwin L.,
RA Whithead S., Dupuy B., Dougan G., Barrell B.and.Parkhill.J.;
RT "The multidrug-resistant human pathogen Clostridium difficile has a highly
RT mobile, mosaic genome.";
RL Nat. Genet. 38:779-786(2006).
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DR EMBL; AM180355; CAJ69367.1; -; Genomic_DNA.
DR RefSeq; WP_009890693.1; NZ_JAUPES010000003.1.
DR RefSeq; YP_001088994.1; NC_009089.1.
DR AlphaFoldDB; Q182G7; -.
DR STRING; 272563.CD630_24800; -.
DR EnsemblBacteria; CAJ69367; CAJ69367; CD630_24800.
DR GeneID; 66354879; -.
DR KEGG; cdf:CD630_24800; -.
DR KEGG; pdc:CDIF630_02727; -.
DR PATRIC; fig|272563.120.peg.2619; -.
DR eggNOG; COG3583; Bacteria.
DR eggNOG; COG3584; Bacteria.
DR OrthoDB; 9798935at2; -.
DR PhylomeDB; Q182G7; -.
DR BioCyc; PDIF272563:G12WB-2635-MONOMER; -.
DR Proteomes; UP000001978; Chromosome.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009254; P:peptidoglycan turnover; IEA:InterPro.
DR CDD; cd14667; 3D_containing_proteins; 1.
DR Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 1.
DR Gene3D; 2.40.40.10; RlpA-like domain; 1.
DR InterPro; IPR010611; 3D_dom.
DR InterPro; IPR007137; DUF348.
DR InterPro; IPR011098; G5_dom.
DR InterPro; IPR036908; RlpA-like_sf.
DR PANTHER; PTHR39160:SF6; CELL WALL SHAPING PROTEIN YABE-RELATED; 1.
DR PANTHER; PTHR39160; CELL WALL-BINDING PROTEIN YOCH; 1.
DR Pfam; PF06725; 3D; 1.
DR Pfam; PF03990; DUF348; 1.
DR Pfam; PF07501; G5; 1.
DR SMART; SM01208; G5; 1.
DR SUPFAM; SSF50685; Barwin-like endoglucanases; 1.
DR PROSITE; PS51109; G5; 1.
DR PROSITE; PS50889; S4; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CAJ69367.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001978};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 84..164
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT REGION 163..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 279 AA; 30468 MW; EAD6056F2A448E03 CRC64;
MNFKKLSNAK VSVMAVVLSV GILSGYSALN KQVTLVVRGE ERTISTFSSN VGDLLESQNI
SYDANDIVTL DENTKLSNGD KIEVIDVKEK TVVETKDIPF EVTVVEDGSL LKGDSKVKEE
GKSGKSELIY KETYHNGKKV EKEFVKKVVK AEPVNKVVSK GTKVEMQVAS SRGESSRRMA
SSSSSSSSSN NGKNMRVVAT AYTGHSITAT GTKPKWGTIA VDPKVIPYGT KVYIPQFDMV
FTAEDCGGAI KGNKIDIYMN DSKTVYNWGR KTIDIRILK
//
