ID RL1_CLOD6 Reviewed; 232 AA.
AC Q18CE9;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2006, sequence version 1.
DT 01-MAY-2013, entry version 55.
DE RecName: Full=50S ribosomal protein L1;
GN Name=rplA; OrderedLocusNames=CD630_00620;
OS Clostridium difficile (strain 630).
OC Bacteria; Firmicutes; Clostridia; Clostridiales;
OC Peptostreptococcaceae.
OX NCBI_TaxID=272563;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=630;
RX PubMed=16804543; DOI=10.1038/ng1830;
RA Sebaihia M., Wren B.W., Mullany P., Fairweather N.F., Minton N.,
RA Stabler R., Thomson N.R., Roberts A.P., Cerdeno-Tarraga A.M., Wang H.,
RA Holden M.T.G., Wright A., Churcher C., Quail M.A., Baker S., Bason N.,
RA Brooks K., Chillingworth T., Cronin A., Davis P., Dowd L., Fraser A.,
RA Feltwell T., Hance Z., Holroyd S., Jagels K., Moule S., Mungall K.,
RA Price C., Rabbinowitsch E., Sharp S., Simmonds M., Stevens K.,
RA Unwin L., Whithead S., Dupuy B., Dougan G., Barrell B., Parkhill J.;
RT "The multidrug-resistant human pathogen Clostridium difficile has a
RT highly mobile, mosaic genome.";
RL Nat. Genet. 38:779-786(2006).
CC -!- FUNCTION: Binds directly to 23S rRNA. The L1 stalk is quite mobile
CC in the ribosome, and is involved in E site tRNA release (By
CC similarity).
CC -!- FUNCTION: Protein L1 is also a translational repressor protein, it
CC controls the translation of the L11 operon by binding to its mRNA
CC (By similarity).
CC -!- SUBUNIT: Part of the 50S ribosomal subunit (By similarity).
CC -!- SIMILARITY: Belongs to the ribosomal protein L1P family.
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DR EMBL; AM180355; CAJ66877.1; -; Genomic_DNA.
DR RefSeq; YP_001086526.1; NC_009089.1.
DR ProteinModelPortal; Q18CE9; -.
DR SMR; Q18CE9; 3-227.
DR STRING; 272563.CD0062; -.
DR EnsemblBacteria; CAJ66877; CAJ66877; CD630_00620.
DR GeneID; 4916675; -.
DR KEGG; cdf:CD630_00620; -.
DR PATRIC; 19438263; VBICloDif38397_0073.
DR eggNOG; COG0081; -.
DR HOGENOM; HOG000207015; -.
DR KO; K02863; -.
DR OMA; YVTSTMG; -.
DR ProtClustDB; PRK05424; -.
DR BioCyc; CDIF272563:GJFE-117-MONOMER; -.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:HAMAP.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:HAMAP.
DR Gene3D; 3.30.190.20; -; 2.
DR Gene3D; 3.40.50.790; -; 1.
DR HAMAP; MF_01318_B; Ribosomal_L1_B; 1; -.
DR InterPro; IPR005878; Ribosom_L1_bac-type.
DR InterPro; IPR002143; Ribosomal_L1.
DR InterPro; IPR016094; Ribosomal_L1_2-a/b-sand.
DR InterPro; IPR016095; Ribosomal_L1_3-a/b-sand.
DR InterPro; IPR023673; Ribosomal_L1_CS.
DR InterPro; IPR023674; Ribosomal_L1_SF.
DR Pfam; PF00687; Ribosomal_L1; 1.
DR PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR SUPFAM; SSF56808; Ribosomal_L1; 1.
DR TIGRFAMs; TIGR01169; rplA_bact; 1.
DR PROSITE; PS01199; RIBOSOMAL_L1; 1.
PE 3: Inferred from homology;
KW Complete proteome; Repressor; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; Translation regulation; tRNA-binding.
FT CHAIN 1 232 50S ribosomal protein L1.
FT /FTId=PRO_0000307992.
SQ SEQUENCE 232 AA; 24807 MW; E70108E13DAB99C8 CRC64;
MAKKGKRYAG ALQKVDRTKF YDASEALTLV SDIAGAKFDE TVEAHIKLGV DSRHADQQVR
GAVVLPHGTG KTKRVLVFAK GEKAKEAEQA GADFVGAEEL VQKIQGENWF DFDIVVATPD
MMGVVGRLGR VLGPKGLMPN PKSGTVTFDV AKAIDEIKAG KVEYRLDKTN IIHVPVGKVS
FGGEKLTENF TALMDAIIKA KPAAAKGQYL RSITVASSMG PGVKINPART AE
//
