ID Q19PJ8_POPTR Unreviewed; 1421 AA.
AC Q19PJ8;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=TIR-NBS type disease resistance protein {ECO:0000313|EMBL:ABF81459.1};
GN ORFNames=POPTR_T002066 {ECO:0000313|EMBL:RQO93048.1};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:ABF81459.1};
RN [1] {ECO:0000313|EMBL:RQO93048.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nisqually-1 {ECO:0000313|EMBL:RQO93048.1};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
RN [2] {ECO:0000313|EMBL:ABF81459.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhang Z.Y., Zhang Q.;
RT "Cloning and characterization of NBS-LRR type of disease resistance-like
RT protein.";
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RQO93048.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Nisqually-1 {ECO:0000313|EMBL:RQO93048.1};
RA Tuskan G., Difazio S., Jansson S., Bohlmann J., Grigoriev I., Hellsten U.,
RA Putnam N., Ralph S., Rombauts S., Salamov A., Schein J., Sterck L.,
RA Aerts A., Bhalerao R., Bhalerao R., Blaudez D., Boerjan W., Brun A.,
RA Brunner A., Busov V., Campbell M., Carlson J., Chalot M., Chapman J.,
RA Chen G., Cooper D., Coutinho P., Couturier J., Covert S., Cronk Q.,
RA Cunningham R., Davis J., Degroeve S., Dejardin A., Depamphilis C.,
RA Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J., Ellis B.,
RA Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A., Gunter L.,
RA Hamberger B., Heinze B., Helariutta Y., Henrissat B., Holligan D., Holt R.,
RA Huang W., Islam-Faridi N., Jones S., Jones-Rhoades M., Jorgensen R.,
RA Joshi C., Kangasjarvi J., Karlsson J., Kelleher C., Kirkpatrick R.,
RA Kirst M., Kohler A., Kalluri U., Larimer F., Leebens-Mack J., Leple J.,
RA Locascio P., Lou Y., Lucas S., Martin F., Montanini B., Napoli C.,
RA Nelson D., Nelson C., Nieminen K., Nilsson O., Pereda V., Peter G.,
RA Philippe R., Pilate G., Poliakov A., Razumovskaya J., Richardson P.,
RA Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J., Schrader J.,
RA Segerman B., Shin H., Siddiqui A., Sterky F., Terry A., Tsai C.,
RA Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S., Yang G.,
RA Yin T., Douglas C., Marra M., Sandberg G., Van De Peer Y., Rokhsar D.;
RT "WGS assembly of Populus trichocarpa.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DQ513245; ABF81459.1; -; mRNA.
DR EMBL; KZ623338; RQO93048.1; -; Genomic_DNA.
DR STRING; 3694.Q19PJ8; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF479; DISEASE RESISTANCE PROTEIN CHL1; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 202..370
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1315..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1315..1378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1421 AA; 161496 MW; 0A59533F499D2802 CRC64;
MVAASSSSSK NDISLGVNQE EHGFTAQRRR AFTVESIYLQ VRGTMEERCF NATSLGREPS
PMELFVETHM RSQDRQKGVQ QFVDNRAQHF VSLRERYRDD PSIHPDFNPD LWMAVGSSGG
LDKNQVYGLS NTTAENLRAA SSASTVGSSQ SKESVALQQH TSHLTEKYEQ LSTNYELRQI
IMNMTSQTAM TEPESSRSIS LGAYDVFLSF RGEDTRKTFT DHLYTALVQA GIHTFRDDDE
LPRGEEISDH LLRAVQESKI SIVVFSKGYA SSRWCLNELV EILKCKNRKT GQIVLPIFYD
IDPSDVRKQN GSFAEAFVKH EERSEEKLVK EWRKALEEAG NLSGRNLNDM ANGHEAKFIK
EIIKDVLNKL DPKYLYVPEH LVGMDRLAHN IFDFLSTATD DVRIVGIHGM PGIGKTTIAK
VVFNQLCYGF EGSCFLSNIN ETPKKLTGLV RLQTQLLRDI LKQDVANFEC VDRGKVLINE
RIRRKRVLFV ADDVARQDQL NALMGERSWF GPGSRVIITT RDSNLLRKAD QTYQIEELTR
DQSLQLFSWH AFKHSKPAED YIELSKDVVD YCGGLPLALE VMGACLYGKN RGGWKSVIDK
LRRIPNHDIQ GKLRISYDSL DGEELRNAFL DIACFFIDRK KRYVAKVLGA RCGYNPEVDL
ETLRGRSLIK VNAIGKITMH DLLRDMGREV VRETSPKEPG KRTRIWNQED AWNVLEQQKG
TDVVEGLALD VRASEAKSLS TRSFAKMKRL NLLQINGAHL TGSFKLLSKE LMWICWLQCP
LKYFSSDFTL DNLAVLDMQY SNLKELWKGQ KILNRLKILN LNHSKNLIKT PNLHSSSLEK
LKLKGCSSLV EVHQSIENLT SLVFLNLEGC WNLKILPESI GNVKSLETLN ISGCSQLEKL
PECMGDMESL TELLADGIEN EQFLTSIGQL KHVRRLSLCG YSSAPPSSSL NSAGVLNWKQ
WLPTSFGWRL VNHLELSNGG LSDRTTNCVD FSGLSALEVL DLTRNKFSSL PSGIGFLPKL
RRLFVLACEY LVSILDLPSS LDCLVASHCK SLKRVRIPIE QKKDLYIELH ESHSLEEIQG
IEGRSNSFWY ICSNQFSHSP KKLQKSVVEV MCNGRHPYRI SPIRGEMPNW MSCSGEGCSL
SFHIPSVFQG LVVWFICPLE PVTIEFDSRI IIIIRNKSNG IQLFEDKRTP GTDMFFIEGF
IRYISISEMG MEDYCGDDEL ELCIYSEPTE HAVRRLPFYP VHIKECGAHV IAKKLNSFEE
SAMGRATVMP SPSLYHLLPH PHCGSITAST PKQWSNYLFA KLQEYNLSLT FHVTRKEKKR
NTGENREGNR EREIDSVERE MTETVETKKT GDIDRETERD RRGEGRKRTK ERRRSAAAGI
GLHSHRHRNT TENVHQHHRQ LSHPRSPPQN VHCARSACKK K
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