ID RLMG_YERPN Reviewed; 395 AA.
AC Q1CMJ1; C4GP13;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 01-MAY-2013, entry version 50.
DE RecName: Full=Ribosomal RNA large subunit methyltransferase G;
DE EC=2.1.1.174;
DE AltName: Full=23S rRNA m2G1835 methyltransferase;
DE AltName: Full=rRNA (guanine-N(2)-)-methyltransferase RlmG;
GN Name=rlmG; OrderedLocusNames=YPN_0457; ORFNames=YP516_0473;
OS Yersinia pestis bv. Antiqua (strain Nepal516).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Yersinia.
OX NCBI_TaxID=377628;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nepal516;
RX PubMed=16740952; DOI=10.1128/JB.00124-06;
RA Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F.,
RA Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
RT "Complete genome sequence of Yersinia pestis strains Antiqua and
RT Nepal516: evidence of gene reduction in an emerging pathogen.";
RL J. Bacteriol. 188:4453-4463(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L.,
RA Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C.,
RA Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C.,
RA Brettin T.S.;
RT "Yersinia pestis Nepal516A whole genome shotgun sequencing project.";
RL Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Specifically methylates the guanine in position 1835
CC (m2G1835) of 23S rRNA (By similarity).
CC -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + guanine(1835) in 23S
CC rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1835) in 23S
CC rRNA.
CC -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmG
CC family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CP000305; ABG16789.1; -; Genomic_DNA.
DR EMBL; ACNQ01000006; EEO78245.1; -; Genomic_DNA.
DR PIR; AB0073; AB0073.
DR RefSeq; YP_646389.1; NC_008149.1.
DR ProteinModelPortal; Q1CMJ1; -.
DR STRING; 377628.YPN_0457; -.
DR EnsemblBacteria; ABG16789; ABG16789; YPN_0457.
DR EnsemblBacteria; EEO78245; EEO78245; YP516_0473.
DR GeneID; 4125798; -.
DR KEGG; ypn:YPN_0457; -.
DR PATRIC; 18599929; VBIYerPes46733_0650.
DR eggNOG; COG2813; -.
DR HOGENOM; HOG000246323; -.
DR KO; K00564; -.
DR OMA; NRHLGYH; -.
DR ProtClustDB; CLSK2502835; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0052916; F:23S rRNA (guanine(1835)-N(2))-methyltransferase activity; IEA:EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR HAMAP; MF_01859; 23SrRNA_methyltr_G; 1; -.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR017237; rRNA_m2G-MeTrfase_RsmD.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR Pfam; PF05175; MTS; 1.
DR PIRSF; PIRSF037565; RRNA_m2G_Mtase_RsmD_prd; 1.
PE 3: Inferred from homology;
KW Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW S-adenosyl-L-methionine; Transferase.
FT CHAIN 1 395 Ribosomal RNA large subunit
FT methyltransferase G.
FT /FTId=PRO_0000366543.
SQ SEQUENCE 395 AA; 43841 MW; E74D17002BA7E5E2 CRC64;
MSQLDLGTQS LELERFPPQE NSNTLQAWEA ADEYLLQNID LSQIDGRPVL VFNDQFGTLA
CALHAYRPFS SSDSYMSQLA TAHNLRLNHL DESAVTLLSS VDDLPEAPKL VVIKIPKALA
LLEHQLRALR RVVAPDTVII AGAKSRDVHN STLQLFEKIL GPTKTTLAWK KARLIHCEVA
DIPLADAPET IDWPLPNTDY IIHNHANVFS RNNLDIGARF FMEILPYDVT GKIADLGCGN
GVVGLIALEQ NPLAEMLFVD ESYMAVASSE LNITVNRPQD LSRCEFMVSH GLAGVERESL
QLVLCNPPFH QQHAVSDHVA WQMFCDAKRC LKAGGELMIV GNRHLDYFHK LKRLFGNCET
LDSNQKFMVL KSVKQASSRS EGGGSGSLDM SYSDF
//
