ID Q1CWG7_MYXXD Unreviewed; 477 AA.
AC Q1CWG7;
DT 11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2006, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE SubName: Full=Sigma-54 dependent DNA-binding response regulator {ECO:0000313|EMBL:ABF86032.1};
GN OrderedLocusNames=MXAN_7143 {ECO:0000313|EMBL:ABF86032.1};
OS Myxococcus xanthus (strain DK1622).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF86032.1, ECO:0000313|Proteomes:UP000002402};
RN [1] {ECO:0000313|EMBL:ABF86032.1, ECO:0000313|Proteomes:UP000002402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA Kaplan H.B.;
RT "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
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DR EMBL; CP000113; ABF86032.1; -; Genomic_DNA.
DR RefSeq; WP_011557062.1; NC_008095.1.
DR AlphaFoldDB; Q1CWG7; -.
DR IntAct; Q1CWG7; 7.
DR STRING; 246197.MXAN_7143; -.
DR EnsemblBacteria; ABF86032; ABF86032; MXAN_7143.
DR GeneID; 41364317; -.
DR KEGG; mxa:MXAN_7143; -.
DR eggNOG; COG2204; Bacteria.
DR HOGENOM; CLU_000445_0_6_7; -.
DR OrthoDB; 9154941at2; -.
DR Proteomes; UP000002402; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF86; TWO COMPONENT SIGNAL TRANSDUCTION SYSTEM SIGMA54-DEPENDENT RESPONSE REGULATOR FIS FAMILY; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:ABF86032.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 24..143
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 172..401
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 73
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 477 AA; 52375 MW; 8AE598FC57F11A6C CRC64;
MVSPVSESAP SLPNPPSAAA RPPCVLVADD QADVLEALRL LLKRDGLTVV TSQSPAGALA
TLEAEDVDLV LMDLNYARDT TSGQEGIDLL GRIRAQDASL PVVVMTAWGS VEGAVEAMRA
GARDYVQKPW DNTRLLATLR TQLELRRALK RSRRLEEENQ HLRRGQGNQL AMVSESRSMQ
PVRRLIERVA PSGANVLVTG EHGTGKEVVA RLIHGGSTRS ERAFVAVNSG GLSEGVFESE
LFGHVKGAFT DAKSDRIGCF ELADGGTLFL DEIGNMPLSQ QAKLLRVLQT GELHPVGSSK
TRRVDVRVVS ATNVDLSRAV AEGRFREDLL YRLNTVEVQL PPLRERREDI PLLAAHFLAE
QGRRYGRPNV RLSSEALEAL LAYAWPGNVR ELEHAVERAM LMASGDEVTQ EDLLLKRAGR
EGMARLEEMT LEEVERYLIE RALARHEGNV SEAAKGLGLS RSALYRRLQY YGIKGAR
//
