ID Q1G7Q4_LACDA Unreviewed; 553 AA.
AC Q1G7Q4;
DT 27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 27-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAI96966.1};
GN OrderedLocusNames=Ldb0125 {ECO:0000313|EMBL:CAI96966.1};
OS Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081
OS / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM
OS 00102 / Lb 14).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=390333 {ECO:0000313|EMBL:CAI96966.1, ECO:0000313|Proteomes:UP000001259};
RN [1] {ECO:0000313|EMBL:CAI96966.1, ECO:0000313|Proteomes:UP000001259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 /
RC NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14
RC {ECO:0000313|Proteomes:UP000001259};
RX PubMed=16754859; DOI=10.1073/pnas.0603024103;
RA van de Guchte M., Penaud S., Grimaldi C., Barbe V., Bryson K., Nicolas P.,
RA Robert C., Oztas S., Mangenot S., Couloux A., Loux V., Dervyn R., Bossy R.,
RA Bolotin A., Batto J.-M., Walunas T., Gibrat J.-F., Bessieres P.,
RA Weissenbach J., Ehrlich S.D., Maguin E.;
RT "The complete genome sequence of Lactobacillus bulgaricus reveals extensive
RT and ongoing reductive evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:9274-9279(2006).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CR954253; CAI96966.1; -; Genomic_DNA.
DR AlphaFoldDB; Q1G7Q4; -.
DR STRING; 390333.Ldb0125; -.
DR KEGG; ldb:Ldb0125; -.
DR PATRIC; fig|390333.13.peg.794; -.
DR eggNOG; COG0169; Bacteria.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_011398_4_0_9; -.
DR Proteomes; UP000001259; Chromosome.
DR GO; GO:0004764; F:shikimate 3-dehydrogenase (NADP+) activity; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.40.50.10860; Leucine Dehydrogenase, chain A, domain 1; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR013708; Shikimate_DH-bd_N.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 2.
DR Pfam; PF08501; Shikimate_dh_N; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001259}.
FT DOMAIN 34..116
FT /note="Shikimate dehydrogenase substrate binding N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08501"
FT DOMAIN 153..196
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 278..519
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 553 AA; 60115 MW; 168DD796ED025DCE CRC64;
MADERNNEIE ETKIQGVNGP ITGWLDGHTI LVGLMAYPIR HTMSPTMHNN AFAKLGLNGA
YLCVEIDNEK LPGAIDAIRP LDMRGSNVSM PNKKKVIPYL DKLDKTSQMC DAVNTIVNEH
GILSGYTTDG MGWVRALKKD GQDVKGKIIT LAGAGGAGLA AATRSLQHDK KVVILEKFPQ
LGGNTARACG PMNAAEPDWQ KGFKALPGEK GTLQELAETP TSEIDPEYVA DFEKLRDQIK
AYLDLGEDYL FDSVLLHEIQ TYLGGKRVDL KGNEIHGKYE LVTTLVNNVL DSVNWLTDLG
VKFDRSDVTM PVGALWRRGH KPVEPMGFAF IHVLGDWVKE HGATVLTETR AKHLIIEGGK
VTGVIAEKTD DSKVTVHAKS VILMAGGFGA NTKMVQKYNT YWSEIADDIA TTNSPAITGD
GIVLGQGAGA ALTGMGFIQL MPVSDPVTGE LFTGLQTPPE NFIMVNQKGE RFVNEFAERD
TLAKAAIDNG GLFYLIADDK IKETAYNTTQ ESIDAQVEAG TLFRADTLEE LAEKVGMDPA
VLTDTIKEVQ LLR
//
