ID   Q1IAG7_PSEE4            Unreviewed;       786 AA.
AC   Q1IAG7;
DT   13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   SubName: Full=Putative multidrug efflux transporter, RND family {ECO:0000313|EMBL:CAK15352.1};
GN   OrderedLocusNames=PSEEN2550 {ECO:0000313|EMBL:CAK15352.1};
OS   Pseudomonas entomophila (strain L48).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=384676 {ECO:0000313|EMBL:CAK15352.1, ECO:0000313|Proteomes:UP000000658};
RN   [1] {ECO:0000313|EMBL:CAK15352.1, ECO:0000313|Proteomes:UP000000658}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L48 {ECO:0000313|EMBL:CAK15352.1,
RC   ECO:0000313|Proteomes:UP000000658};
RX   PubMed=16699499; DOI=10.1038/nbt1212;
RA   Vodovar N., Vallenet D., Cruveiller S., Rouy Z., Barbe V., Acosta C.,
RA   Cattolico L., Jubin C., Lajus A., Segurens B., Vacherie B., Wincker P.,
RA   Weissenbach J., Lemaitre B., Medigue C., Boccard F.;
RT   "Complete genome sequence of the entomopathogenic and metabolically
RT   versatile soil bacterium Pseudomonas entomophila.";
RL   Nat. Biotechnol. 24:673-679(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CT573326; CAK15352.1; -; Genomic_DNA.
DR   RefSeq; WP_011533749.1; NC_008027.1.
DR   AlphaFoldDB; Q1IAG7; -.
DR   STRING; 384676.PSEEN2550; -.
DR   GeneID; 32805713; -.
DR   KEGG; pen:PSEEN2550; -.
DR   eggNOG; COG1033; Bacteria.
DR   HOGENOM; CLU_008861_4_0_6; -.
DR   OrthoDB; 9176717at2; -.
DR   Proteomes; UP000000658; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF10; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        231..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        257..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        369..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        618..636
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        641..659
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        665..690
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        711..734
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        746..773
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          255..382
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   DOMAIN          651..768
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   786 AA;  85320 MW;  C767AFD2E8F73173 CRC64;
     MLAYLVSALE RLVFRHRLAT LGLLAVVTLV MGLFAARLEM SAGFDKQLPQ QHPYIKTFNQ
     YRDVLFGANR VIVVLRARHG DIWNPAALTR LHDLTQTLFF LPGIDRRSVT SLWTPNTRAV
     QITEEGMKAE DVVGGDVTVG NLDARAIAGI RERTLAGGFV GSLVANDQRG AMVVAELADP
     DPATGKRLDY LAFSRQLEEQ VRAQYANTDF DVQIIGFAKQ MGDIGAGARS VVEFFALAFV
     LTALAVYWYT RSWRLTVLPL VCSLVSVAWQ FGTLTLLGFG LDPLAILVPF LVFAIGVSHG
     VQQVNFIAKE VCAGADGMTA ARRSFVGLMI PGTLALITAF VGFATLVLVP IPMIRELAIT
     ASVGVAYKIV TNLVMLPVLA SYCCFDSRYV ARVERLRARR EGLMTGLGRI AEPRNAVLVA
     LLGAVLMVLA VWQSQGRHVG HVLPGAPELH ADSRYNQDVE QVVGHFALGL DLFTVAVQTP
     AGGCYRHDVM AYVDRLTWYL GTLPGVLSAQ SLPAMAKLAA SGVNEGQPKW AALPVDELSL
     GEAVRQVPEA LRLYDADCTV LPVNLYLADH KASTLKQVTA AIEQYRERYV LPGVNVRLAS
     GNAGVQAATN AVVEGSELPM MLYVYLTIVL LVGLVYRDWR AMLACCLPLT LATFLGYWFM
     KALDIGLTVA TLPVMVLAVG VGVDYAFYIY NRLQLHLAAG RDIVAAFQQA LREVGVATVF
     TALTLSVGVA TWSFSALKFQ ADMGLLLTFM FMANMLMAVT LLPALAVVLE ILVPRRGPVR
     APLVAH
//