ID Q1ITC3_KORVE Unreviewed; 501 AA.
AC Q1ITC3;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Fe-S protein, radical SAM family {ECO:0000313|EMBL:ABF39877.1};
GN OrderedLocusNames=Acid345_0874 {ECO:0000313|EMBL:ABF39877.1};
OS Koribacter versatilis (strain Ellin345).
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Koribacter.
OX NCBI_TaxID=204669 {ECO:0000313|EMBL:ABF39877.1, ECO:0000313|Proteomes:UP000002432};
RN [1] {ECO:0000313|EMBL:ABF39877.1, ECO:0000313|Proteomes:UP000002432}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ellin345 {ECO:0000313|EMBL:ABF39877.1,
RC ECO:0000313|Proteomes:UP000002432};
RX PubMed=19201974; DOI=10.1128/AEM.02294-08;
RA Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M.,
RA Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B.,
RA Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C.,
RA Davidsen T.M., DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S.,
RA Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P.,
RA Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q.,
RA Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R.,
RA Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R.;
RT "Three genomes from the phylum Acidobacteria provide insight into the
RT lifestyles of these microorganisms in soils.";
RL Appl. Environ. Microbiol. 75:2046-2056(2009).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP000360; ABF39877.1; -; Genomic_DNA.
DR RefSeq; WP_011521679.1; NC_008009.1.
DR AlphaFoldDB; Q1ITC3; -.
DR STRING; 204669.Acid345_0874; -.
DR EnsemblBacteria; ABF39877; ABF39877; Acid345_0874.
DR KEGG; aba:Acid345_0874; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_4_3_0; -.
DR OrthoDB; 100851at2; -.
DR Proteomes; UP000002432; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000002432}.
FT DOMAIN 4..139
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 182..414
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 501 AA; 56359 MW; DBF1179256BE2B5D CRC64;
MLTRGKVVLF YPAYEGAPLS APTCLLSLAA TLREHDYSVV MIDAAIVPNS KDRVLRELDD
ALCLGISVLT GPMILGAIEV AKAAKELHAK LPIVFGGWHP TLLPEQTLIE PYVDFVVRRQ
GESSFLELVN AIASGQSGEF ISGVSWKIRD HCEHNVDRPT QPLDALPLPA YDMVDFDAYE
RTAGERKLAY ATSVGCPYAC NYCTDMVFYK RRFNALNAER VVAEMTGLVA KFKIAEIALL
DSNFPVDVKR AVAIARGIYE SGVPFRWTFQ ASTDFLFRMS DDEVKVLRAS GVSHMGFGTE
STSESVLKLM NKRHQRMNEV YETARKADAA GIRVTFNLIF GYPGETENDR AETFRAMSEI
AREFQSVSFS PNIFTPYPGI PIWPELREMG VQEPQSLREW ALLPLGVNVL PWLQGRDLAR
LQRMLAYFLL NSHVRKNSRS ISRASRVVRR AVSGSVRWRI RKSRFSFPWE LWLARTTEHW
AERRSLVTGQ VLPKPSAAVC N
//
