ID Q1J476_STRPF Unreviewed; 122 AA.
AC Q1J476;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Cadmium efflux system accessory protein {ECO:0000313|EMBL:ABF38885.1};
GN Name=cadC {ECO:0000313|EMBL:ABF38885.1};
GN OrderedLocusNames=MGAS10750_Spy1935 {ECO:0000313|EMBL:ABF38885.1};
OS Streptococcus pyogenes serotype M4 (strain MGAS10750).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=370554 {ECO:0000313|EMBL:ABF38885.1, ECO:0000313|Proteomes:UP000002434};
RN [1] {ECO:0000313|EMBL:ABF38885.1, ECO:0000313|Proteomes:UP000002434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGAS10750 {ECO:0000313|EMBL:ABF38885.1,
RC ECO:0000313|Proteomes:UP000002434};
RX PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA Musser J.M.;
RT "Molecular genetic anatomy of inter- and intraserotype variation in the
RT human bacterial pathogen group A Streptococcus.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
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DR EMBL; CP000262; ABF38885.1; -; Genomic_DNA.
DR AlphaFoldDB; Q1J476; -.
DR KEGG; spi:MGAS10750_Spy1935; -.
DR HOGENOM; CLU_097806_7_3_9; -.
DR Proteomes; UP000002434; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR018334; ArsR_HTH.
DR InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; NF033788; HTH_metalloreg; 1.
DR PANTHER; PTHR43132; ARSENICAL RESISTANCE OPERON REPRESSOR ARSR-RELATED; 1.
DR PANTHER; PTHR43132:SF6; TRANSCRIPTIONAL REPRESSOR SMTB HOMOLOG; 1.
DR Pfam; PF01022; HTH_5; 1.
DR PRINTS; PR00778; HTHARSR.
DR SMART; SM00418; HTH_ARSR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00846; HTH_ARSR_1; 1.
DR PROSITE; PS50987; HTH_ARSR_2; 1.
PE 4: Predicted;
KW Cadmium resistance {ECO:0000256|ARBA:ARBA00043263};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 34..122
FT /note="HTH arsR-type"
FT /evidence="ECO:0000259|PROSITE:PS50987"
SQ SEQUENCE 122 AA; 14159 MW; 508A0369251DD783 CRC64;
MGCVRLGENI MKKDSICQVN VINQQNVITA TNYLEKEKVQ KSLRILSKFT DNKQINIIFY
LLTVEELCVC DIACLLNLSM ASASHHLRKL ANQNILDTRR EGKIIYYFIK DEEIRDFFNQ
LG
//
