ID Q1J4G7_STRPF Unreviewed; 422 AA.
AC Q1J4G7;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Periplasmic component of efflux system {ECO:0000313|EMBL:ABF38769.1};
GN OrderedLocusNames=MGAS10750_Spy1819 {ECO:0000313|EMBL:ABF38769.1};
OS Streptococcus pyogenes serotype M4 (strain MGAS10750).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=370554 {ECO:0000313|EMBL:ABF38769.1, ECO:0000313|Proteomes:UP000002434};
RN [1] {ECO:0000313|EMBL:ABF38769.1, ECO:0000313|Proteomes:UP000002434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGAS10750 {ECO:0000313|EMBL:ABF38769.1,
RC ECO:0000313|Proteomes:UP000002434};
RX PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA Musser J.M.;
RT "Molecular genetic anatomy of inter- and intraserotype variation in the
RT human bacterial pathogen group A Streptococcus.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
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DR EMBL; CP000262; ABF38769.1; -; Genomic_DNA.
DR RefSeq; WP_011285226.1; NC_008024.1.
DR AlphaFoldDB; Q1J4G7; -.
DR KEGG; spi:MGAS10750_Spy1819; -.
DR HOGENOM; CLU_018816_14_5_9; -.
DR Proteomes; UP000002434; Chromosome.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
PE 4: Predicted;
FT DOMAIN 62..291
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 286..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 46594 MW; 272ED0A63229D12B CRC64;
MFQLRKKMTR KQLALLSAGV LTCVVGGSYL IMNHQQQEIV SSVNKVKALT IKEAMEQGKD
ISLTLAGEVT ANNSSKVKID SSKGEVKDVF VKKGDVVKVG QPLFSYETSQ RLTAQSSEFD
VQTKANQLQV AKTNAALKWE TYNRKVNEIN TLKSRYNTAP DESLLEQIRS AEDSVSQALS
DAKTADSDVK TAQIELDKAN ATATTEKGKL EYDTVKSDTA GTIVSLNTDL PNQSKSKKEN
ETFMEIIDKS KMLVKGNISE FDRDKLKIGQ KVEVIDRKDN SKKWTGKVTQ VGNLKAEEKG
QGQGQGGNDQ QDNPNQAKFP YVIELDQSDK QPLIGSHTYV NVLNNVPEAG KIVLKETFTM
AENGKTYVWK VDKNKVKKQE IKTKPFSKGY VEVTSGLTMQ DKIAQPLPGM KDGMEVGSIV
KP
//
