ID   Q1JFZ0_STRPD            Unreviewed;       142 AA.
AC   Q1JFZ0;
DT   13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Acetyltransferase {ECO:0000313|EMBL:ABF34354.1};
DE            EC=2.3.1.- {ECO:0000313|EMBL:ABF34354.1};
GN   OrderedLocusNames=MGAS10270_Spy1289 {ECO:0000313|EMBL:ABF34354.1};
OS   Streptococcus pyogenes serotype M2 (strain MGAS10270).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=370552 {ECO:0000313|EMBL:ABF34354.1, ECO:0000313|Proteomes:UP000002436};
RN   [1] {ECO:0000313|EMBL:ABF34354.1, ECO:0000313|Proteomes:UP000002436}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGAS10270 {ECO:0000313|EMBL:ABF34354.1,
RC   ECO:0000313|Proteomes:UP000002436};
RX   PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA   Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA   Musser J.M.;
RT   "Molecular genetic anatomy of inter- and intraserotype variation in the
RT   human bacterial pathogen group A Streptococcus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
CC   -!- SIMILARITY: Belongs to the acetyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00008694}.
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DR   EMBL; CP000260; ABF34354.1; -; Genomic_DNA.
DR   RefSeq; WP_011054720.1; NC_008022.1.
DR   AlphaFoldDB; Q1JFZ0; -.
DR   SMR; Q1JFZ0; -.
DR   KEGG; sph:MGAS10270_Spy1289; -.
DR   HOGENOM; CLU_056607_9_0_9; -.
DR   Proteomes; UP000002436; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   Gene3D; 3.40.630.30; -; 1.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF13673; Acetyltransf_10; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:ABF34354.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000313|EMBL:ABF34354.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        121..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..120
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
SQ   SEQUENCE   142 AA;  16034 MW;  B575CD6FC4CE0ECA CRC64;
     MADKFDANDE TRTVYAVVYD NDQPVSTGQF LAETKIEARL TRIVTLADYC GCGYGAKVTE
     ALETYTRREG FYQLTIHSEL TAQTFYENLG YQTYGPKCLE DGEYCQSLAK TILKWEKNMD
     IAMLIAIVGG LLGCYLYLTK NN
//