ID Q1JK80_STRPC Unreviewed; 314 AA.
AC Q1JK80;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Magnesium and cobalt transport protein {ECO:0000313|EMBL:ABF32743.1};
GN Name=corA {ECO:0000313|EMBL:ABF32743.1};
GN OrderedLocusNames=MGAS9429_Spy1556 {ECO:0000313|EMBL:ABF32743.1};
OS Streptococcus pyogenes serotype M12 (strain MGAS9429).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=370551 {ECO:0000313|EMBL:ABF32743.1, ECO:0000313|Proteomes:UP000002433};
RN [1] {ECO:0000313|EMBL:ABF32743.1, ECO:0000313|Proteomes:UP000002433}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGAS9429 {ECO:0000313|EMBL:ABF32743.1,
RC ECO:0000313|Proteomes:UP000002433};
RX PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA Musser J.M.;
RT "Molecular genetic anatomy of inter- and intraserotype variation in the
RT human bacterial pathogen group A Streptococcus.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; CP000259; ABF32743.1; -; Genomic_DNA.
DR RefSeq; WP_002983147.1; NC_008021.1.
DR AlphaFoldDB; Q1JK80; -.
DR GeneID; 69900289; -.
DR KEGG; spk:MGAS9429_Spy1556; -.
DR HOGENOM; CLU_007127_8_1_9; -.
DR Proteomes; UP000002433; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12827; EcCorA_ZntB-like_u2; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR047199; CorA-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR47891:SF2; MAGNESIUM AND COBALT TRANSPORTER; 1.
DR PANTHER; PTHR47891; TRANSPORTER-RELATED; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 255..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 314 AA; 36614 MW; 9B0A844DA3E186B4 CRC64;
MKQMFLSSAI EFKEIETFEP GAWIKLVNPS QEESMKIADQ FNIDISDLRA PLDVEETSRI
AVEDDYTLII VDVPIYEERN NKSYYITMPL GIIVTENAVI TTCLHDMTLF DHFHNRRVKN
FYTFMKTRFV FQILYRNAEL FLTALRTIDR QSERLEAQLE AATRNEELID MMELEKSIVY
LKASLKFNER IVKKLSSSTS SLKKYIEDED LLEDTLIETQ QAIEMAGIYE NVLNAMTETT
ASIINNNQNT IMKTLALMTM ALDIPTVIFS AYGMNFQNNW LPLNGLEHAF WYITLIAMLL
SSFVVIYFIR KKWF
//
