ID Q1JMP5_STRPC Unreviewed; 213 AA.
AC Q1JMP5;
DT 13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2006, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Galactose-6-phosphate isomerase subunit {ECO:0000313|EMBL:ABF31704.1};
DE EC=5.3.1.26 {ECO:0000313|EMBL:ABF31704.1};
GN OrderedLocusNames=MGAS9429_Spy0516 {ECO:0000313|EMBL:ABF31704.1};
OS Streptococcus pyogenes serotype M12 (strain MGAS9429).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=370551 {ECO:0000313|EMBL:ABF31704.1, ECO:0000313|Proteomes:UP000002433};
RN [1] {ECO:0000313|EMBL:ABF31704.1, ECO:0000313|Proteomes:UP000002433}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGAS9429 {ECO:0000313|EMBL:ABF31704.1,
RC ECO:0000313|Proteomes:UP000002433};
RX PubMed=16636287; DOI=10.1073/pnas.0510279103;
RA Beres S.B., Richter E.W., Nagiec M.J., Sumby P., Porcella S.F., DeLeo F.R.,
RA Musser J.M.;
RT "Molecular genetic anatomy of inter- and intraserotype variation in the
RT human bacterial pathogen group A Streptococcus.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:7059-7064(2006).
CC -!- SIMILARITY: Belongs to the LacAB/RpiB family.
CC {ECO:0000256|ARBA:ARBA00008754}.
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DR EMBL; CP000259; ABF31704.1; -; Genomic_DNA.
DR RefSeq; WP_002990512.1; NC_008021.1.
DR AlphaFoldDB; Q1JMP5; -.
DR KEGG; spk:MGAS9429_Spy0516; -.
DR HOGENOM; CLU_112772_0_0_9; -.
DR Proteomes; UP000002433; Chromosome.
DR GO; GO:0050044; F:galactose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0005988; P:lactose metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1400.10; Sugar-phosphate isomerase, RpiB/LacA/LacB; 1.
DR InterPro; IPR022133; Ribose_5_isomerase_C.
DR InterPro; IPR003500; RpiB_LacA_LacB.
DR InterPro; IPR036569; RpiB_LacA_LacB_sf.
DR PANTHER; PTHR30345:SF6; RIBOSE 5-PHOSPHATE ISOMERASE-RELATED; 1.
DR PANTHER; PTHR30345; RIBOSE-5-PHOSPHATE ISOMERASE B; 1.
DR Pfam; PF12408; DUF3666; 1.
DR Pfam; PF02502; LacAB_rpiB; 1.
DR SUPFAM; SSF89623; Ribose/Galactose isomerase RpiB/AlsB; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:ABF31704.1};
KW Lactose metabolism {ECO:0000256|ARBA:ARBA00022736}.
FT DOMAIN 164..210
FT /note="Ribose-5-phosphate isomerase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12408"
SQ SEQUENCE 213 AA; 23190 MW; 9E2866F807F68BC3 CRC64;
MKIALINENS QAAKNGIIYD ALTSVTDKHG YQVFNYGMYG TEGESQLTYV QNGLLASILL
TTKAADFVVT GCGTGVGAML ALNSFPGVTC GFASEPTEAY LFSQINGGNA LSIPFAKGFG
WGAELNLTLI FERLFAEPMG GGYPKERAIP EQRNARILSD LKKITYRDLL AIVKDIDQDF
LKETISGAHF KEYFFANAEP SELVAYLKSV LEQ
//
