ID Q1L581_TASV2 Unreviewed; 240 AA.
AC Q1L581;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 30-MAY-2006, sequence version 1.
DT 08-NOV-2023, entry version 63.
DE RecName: Full=Non-structural polyprotein 1AB {ECO:0000256|ARBA:ARBA00019743};
DE Flags: Fragment;
OS Turkey astrovirus 2 (TAstV-2).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC Stellavirales; Astroviridae; Avastrovirus; Avastrovirus 3.
OX NCBI_TaxID=246343 {ECO:0000313|EMBL:AAZ31499.1};
OH NCBI_TaxID=9103; Meleagris gallopavo (Wild turkey).
RN [1] {ECO:0000313|EMBL:AAZ31499.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CA/SEP-A269/04 {ECO:0000313|EMBL:AAZ31499.1};
RX PubMed=16604451; DOI=10.1007/s11262-005-6875-3;
RA Pantin-Jackwood M.J., Spackman E., Woolcock P.R.;
RT "Phylogenetic analysis of Turkey astroviruses reveals evidence of
RT recombination.";
RL Virus Genes 32:187-192(2006).
CC -!- FUNCTION: Contains the viral protease participating in the cleavage of
CC the polyprotein into functional products. It contains also the
CC activities necessary for replication of genomic RNA, as well as
CC transcription of subgenomic mRNA. {ECO:0000256|ARBA:ARBA00029407}.
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000256|ARBA:ARBA00004301};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004301}.
CC -!- SIMILARITY: Belongs to the astroviridae polyprotein 1AB family.
CC {ECO:0000256|ARBA:ARBA00005873}.
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DR EMBL; DQ066576; AAZ31499.1; -; Genomic_RNA.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR CDD; cd23172; ps-ssRNAv_Astroviridae_RdRp; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Ribosomal frameshifting {ECO:0000256|ARBA:ARBA00022758};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 20..154
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAZ31499.1"
FT NON_TER 240
FT /evidence="ECO:0000313|EMBL:AAZ31499.1"
SQ SEQUENCE 240 AA; 28085 MW; E331888A2259C2E8 CRC64;
TPFFGGLDRR VRRLCGDGDR YFVEMDWTRY DGTIPKSLFW RIRQIRFFFL HDSHKTPKMR
RLYNWYVKNL LEKIILLPTG EVCQVKKGNP SGQYSTTVDN NMINVWLTTF EVSYLFFKQR
GRLPTEKELQ ENCSMICYGD DRLLSIRKGF VEYEPDTVIE MYKNIFGMWV KRNNIKIQDT
PEGLSFCGLT IVKSNTGAYV GVPNVNKILS TLENPVRRLP DVESLWGKLV SLRILCENAP
//
