ID Q1LX89_DANRE Unreviewed; 368 AA.
AC Q1LX89; A0A8M1N596;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 2.
DT 27-MAR-2024, entry version 116.
DE SubName: Full=Ankyrin repeat domain 16 {ECO:0000313|Ensembl:ENSDARP00000029899};
DE SubName: Full=Ankyrin repeat domain-containing protein 16 {ECO:0000313|RefSeq:NP_001017563.2};
GN Name=ankrd16 {ECO:0000313|Ensembl:ENSDARP00000029899,
GN ECO:0000313|RefSeq:NP_001017563.2,
GN ECO:0000313|ZFIN:ZDB-GENE-041210-253};
GN Synonyms=si:dkey-108d22.7 {ECO:0000313|RefSeq:NP_001017563.2},
GN zgc:110558 {ECO:0000313|RefSeq:NP_001017563.2};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000029899};
RN [1] {ECO:0000313|RefSeq:NP_001017563.2}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20587335;
RA Chen S., Zeng M., Sun H., Deng W., Lu Y., Tao D., Liu Y., Zhang S., Ma Y.;
RT "Zebrafish Dnd protein binds to 3'UTR of geminin mRNA and regulates its
RT expression.";
RL BMB Rep. 43:438-444(2010).
RN [2] {ECO:0000313|Ensembl:ENSDARP00000029899, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000029899};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|Ensembl:ENSDARP00000029899}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000029899};
RG Ensembl;
RL Submitted (AUG-2013) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:NP_001017563.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX469931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001017563.2; NM_001017563.2.
DR STRING; 7955.ENSDARP00000029899; -.
DR PaxDb; 7955-ENSDARP00000029899; -.
DR Ensembl; ENSDART00000037600; ENSDARP00000029899; ENSDARG00000003822.
DR Ensembl; ENSDART00000037600.7; ENSDARP00000029899.6; ENSDARG00000003822.8.
DR GeneID; 550225; -.
DR KEGG; dre:550225; -.
DR AGR; ZFIN:ZDB-GENE-041210-253; -.
DR CTD; 54522; -.
DR ZFIN; ZDB-GENE-041210-253; ankrd16.
DR eggNOG; KOG0504; Eukaryota.
DR HOGENOM; CLU_000134_48_2_1; -.
DR OMA; WTAFHIT; -.
DR OrthoDB; 167463at2759; -.
DR PhylomeDB; Q1LX89; -.
DR TreeFam; TF329520; -.
DR Proteomes; UP000000437; Alternate scaffold 4.
DR Proteomes; UP000000437; Chromosome 4.
DR Bgee; ENSDARG00000003822; Expressed in gastrula and 22 other cell types or tissues.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 9.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 6.
PE 1: Evidence at protein level;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q1LX89};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT REPEAT 44..66
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 78..110
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 111..143
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 178..201
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 281..313
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 314..346
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 368 AA; 40937 MW; 06AC24D88FE5D9E4 CRC64;
MEEENTVKLL IKAVQHGELC TVKQHLNDLA DNKQTVIYTH FGKSGDTVLH YAARHGHVDI
LRYLVEELNM DIEVYNSDYK RALHEASSMG HYECVRFLIC RGAKVDSLKK ADWTPLMMAC
TRRNLEVIQE LLDYGADPTL QNKDGWSSFH IACREGDPAI INHLLLAKPD IWKTKSKTGR
TPLHTAAMHG CEDAVKILLQ RCCYEPDEKD SCGVTPFMDA IRNGHIAVAK LLLEDHQASP
SAVDILGAQP LHQASVTAQE EALSFLVHHL GMDINSRATK LELTALHYAA KEGHTSTIKT
LLALGADLHA RDAKGRSALH MACIGQHVDT VRMLLQMGLT DTEDNTGNTA RQYAIKPHIK
DVFENLGI
//
