ID Q1NCP8_SPHSS Unreviewed; 488 AA.
AC Q1NCP8;
DT 30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 30-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=4-hydroxyphenylacetate 3-hydroxylase {ECO:0000313|EMBL:EAT08842.1};
GN ORFNames=SKA58_16728 {ECO:0000313|EMBL:EAT08842.1};
OS Sphingomonas sp. (strain SKA58).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=314266 {ECO:0000313|EMBL:EAT08842.1, ECO:0000313|Proteomes:UP000005395};
RN [1] {ECO:0000313|EMBL:EAT08842.1, ECO:0000313|Proteomes:UP000005395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SKA58 {ECO:0000313|EMBL:EAT08842.1,
RC ECO:0000313|Proteomes:UP000005395};
RA Hagstrom A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAT08842.1}.
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DR EMBL; AAQG01000007; EAT08842.1; -; Genomic_DNA.
DR RefSeq; WP_009823089.1; NZ_CH959307.1.
DR AlphaFoldDB; Q1NCP8; -.
DR STRING; 314266.SKA58_16728; -.
DR eggNOG; COG2368; Bacteria.
DR HOGENOM; CLU_023920_2_1_5; -.
DR OrthoDB; 7233724at2; -.
DR Proteomes; UP000005395; Unassembled WGS sequence.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005395}.
FT DOMAIN 3..268
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 277..474
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 150..153
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 187
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 488 AA; 53565 MW; 68C7CCF727E88880 CRC64;
MKTGSQHLAT LRDGRSIYID GKLAGDVTQH PAFCNSVASA ARLYDFQAAN PDLMTFTSPS
SGERVNRAWD LPTDYEGLVM RRKAMEAWAG THYGFMGRSP DHVASCFAGM MMGIDLFENH
DRARAGALAD YFRYARDNDL FLTYVIINPQ ADRSKSAHEQ ADPYLTAGIV DEDSTGITIR
GAKMLATSGI MANEVFVSCV QPLGVGDEKY AISLAVPMNA PGVKLLSRKS YEAASPSQFD
NPLASRFDEN DAVIYFDDVK VPWDRVFIAG DTAMVMKQFH ATPAHVLQNY QCQVRLMVKM
RFLMGIARRT AEINGTLALP PVRDMLGQLA AEAALVEGMV HGMEAKGKVR NGYYIPDGHL
LYASQVLTQQ LYSKVITSLR DLAGGGLIML PSSIADFVNP ETAALIGKTQ QSPVANSQDR
VKFFKLAWDA IGSEFASRHN QYEMFYAGAT FVTKGHSFRT FDWESSTNLV DTMLASYDLH
DAGMGVAA
//
