GenomeNet

Database: UniProt
Entry: Q1NWF3_9DELT
LinkDB: Q1NWF3_9DELT
Original site: Q1NWF3_9DELT 
ID   Q1NWF3_9DELT            Unreviewed;       447 AA.
AC   Q1NWF3;
DT   30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT   30-MAY-2006, sequence version 1.
DT   28-MAR-2018, entry version 73.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=MldDRAFT_0845 {ECO:0000313|EMBL:EAT06011.1};
OS   delta proteobacterium MLMS-1.
OC   Bacteria; Proteobacteria; Deltaproteobacteria.
OX   NCBI_TaxID=262489 {ECO:0000313|EMBL:EAT06011.1, ECO:0000313|Proteomes:UP000005853};
RN   [1] {ECO:0000313|EMBL:EAT06011.1, ECO:0000313|Proteomes:UP000005853}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MLMS-1 {ECO:0000313|EMBL:EAT06011.1,
RC   ECO:0000313|Proteomes:UP000005853};
RG   US DOE Joint Genome Institute (JGI-ORNL);
RA   Larimer F., Land M., Hauser L.;
RT   "Annotation of the draft genome assembly of delta proteobacterium
RT   MLMS-1.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EAT06011.1, ECO:0000313|Proteomes:UP000005853}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MLMS-1 {ECO:0000313|EMBL:EAT06011.1,
RC   ECO:0000313|Proteomes:UP000005853};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Bruce D.,
RA   Pitluck S., Richardson P.;
RT   "Sequencing of the draft genome and assembly of delta proteobacterium
RT   MLMS-1.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAT06011.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AAQF01000013; EAT06011.1; -; Genomic_DNA.
DR   RefSeq; WP_007291407.1; NZ_AAQF01000013.1.
DR   ProteinModelPortal; Q1NWF3; -.
DR   EnsemblBacteria; EAT06011; EAT06011; MldDRAFT_0845.
DR   PATRIC; fig|262489.9.peg.5851; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000005853; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005853};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005853}.
FT   DOMAIN      352    420       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     148    155       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   447 AA;  49990 MW;  61FE74E492DF9D0A CRC64;
     MIWPEVRKIL HQRLPESVFN LWIEPLSCLQ EGDGRLELAG PDRFFCNWVA ENHLADIQAA
     LAEVGRQGLE VRFQVDGQAG ASDEEAGKGA EQLRLPRMPR NHNRIRTLHP RYTFDEFMVG
     DSNALAYSAC EAIATGTTQA EPCVFINAGT GLGKSHLTHA VAHHLYNNAP GTRLCCLTSQ
     QLTAELVHHI RNNSMEQFKE KFQRRCDVLL VEDVQTLSGR SKTQVELAEA VDSLLDSGRR
     VLFTGSRSPR EIPDLDEGVR SRLASGLVTT INPPDIKTRR LIIRRKAVFH KLALDEEMVA
     YIAEKVRGDI RKVESAMVGL KAKANLRRVA PTMEMVREVV ATVAGEETPG LNSEAIRDFV
     AAQFKLSVEE LRSKSRKKEI TFPRQVSMYL ARKLTDEGLA GIGKAFDRDH STVVHSIRVI
     NEAVARNGSV RGQIEHLTKR LRQRDQG
//
DBGET integrated database retrieval system