ID Q1QM20_NITHX Unreviewed; 897 AA.
AC Q1QM20;
DT 16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=GCN5-related N-acetyltransferase {ECO:0000313|EMBL:ABE62727.1};
GN OrderedLocusNames=Nham_1919 {ECO:0000313|EMBL:ABE62727.1};
OS Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Nitrobacter.
OX NCBI_TaxID=323097 {ECO:0000313|EMBL:ABE62727.1, ECO:0000313|Proteomes:UP000001953};
RN [1] {ECO:0000313|EMBL:ABE62727.1, ECO:0000313|Proteomes:UP000001953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10229 / NCIMB 13809 / X14
RC {ECO:0000313|Proteomes:UP000001953};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L.,
RA O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T.,
RA Gentry M.E., Bruce D., Richardson P.;
RT "Complete sequence of chromosome of Nitrobacter hamburgensis X14.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000319; ABE62727.1; -; Genomic_DNA.
DR RefSeq; WP_011510407.1; NC_007964.1.
DR AlphaFoldDB; Q1QM20; -.
DR STRING; 323097.Nham_1919; -.
DR KEGG; nha:Nham_1919; -.
DR eggNOG; COG0456; Bacteria.
DR eggNOG; COG1042; Bacteria.
DR HOGENOM; CLU_007415_0_2_5; -.
DR OrthoDB; 9807426at2; -.
DR Proteomes; UP000001953; Chromosome.
DR GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR043938; Ligase_CoA_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF19045; Ligase_CoA_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001953};
KW Transferase {ECO:0000313|EMBL:ABE62727.1};
KW Tricarboxylic acid cycle {ECO:0000256|ARBA:ARBA00022532}.
FT DOMAIN 744..897
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 897 AA; 96308 MW; BC2F1B175A430FE3 CRC64;
MSTYRLNSLL SPNSVALVGA STHSGSVGRA IIKNIRASRF GGPFGVVNSH YREIDGIATV
KRLAKLPFVP ELVIVTTPAA TVPEIVAEAG QLGSAGVIIV SAGLGHGAGS LAEAAERAAR
AYHMRLIGPN CLGILMPTIN LNASFAAHMP RAGNLALISQ SGAIATGMVD WAARRNVGFS
GIVSVGDQLD VDIADLLEFF ALDTDTKAIL MYIEAVKDAR KFMSAARAAA RVKPVVVVKS
GRMAQGAKAA ATHTGALAGS DAVYDAAFRR AGILRVFDLR ELFDCAETLS RVKFAFGKRL
AMLTNGGGIG VLAVDRLIEL GGIPAALNPV VKQQLDAVLP VTWSGSNPVD IIGDADPARY
VAALEILLED GDSDAVLVMN VQTAIADSGA IATAVTRAVD ADRRKHTVSA KPVLAVWVGA
DEKISRTFTD AGIPDFPTED DAVRGFMHLV HHREVVESLA AVPPSLAHEF VPDTEAARRV
VESAVAEGRG WLDPIEVMGV LDAYGIASVP TRAAANAEEA AAHAESLFAQ GATVVLKVLS
RDISHKSDVG GVVLNLTSVD SVRAAVLRIL ASAKAKRPDA RIDGFMVQPM ILRPKARELI
LGIASDPTFG SVIVFGHGGT AVEVINDKAL ALPPLDLKLA RDLVERTRVS RLLRAYRDVP
PVKQDEIPLT LVKLAQLAAD IPEISELDLN PLLADETGVL TVDARIAVGP PMRKFIGPGN
ANFAVRPYPS QWLRHLVLKD NWRIMVRPIR PDDEPLISDF LRHITKEDLR FRFFAAIKPL
NHEFIARLTQ LDYARAMAFV AFDEVTNEMV GVVRIHSDSI YETGEYAILL RSDLKGRGLG
WMLMQLIIEY ARSEGLKYIA GDVLAENTVM LAMCRDLGFE IVNDPVEHDI FHVRLVL
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