ID Q1RD15_ECOUT Unreviewed; 380 AA.
AC Q1RD15;
DT 16-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Prophage lambda integrase {ECO:0000313|EMBL:ABE06749.1};
GN OrderedLocusNames=UTI89_C1267 {ECO:0000313|EMBL:ABE06749.1};
OS Escherichia coli (strain UTI89 / UPEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=364106 {ECO:0000313|EMBL:ABE06749.1, ECO:0000313|Proteomes:UP000001952};
RN [1] {ECO:0000313|EMBL:ABE06749.1, ECO:0000313|Proteomes:UP000001952}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTI89 / UPEC {ECO:0000313|Proteomes:UP000001952};
RX PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA Chen S.L., Hung C.S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA Gordon J.I.;
RT "Identification of genes subject to positive selection in uropathogenic
RT strains of Escherichia coli: a comparative genomics approach.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; CP000243; ABE06749.1; -; Genomic_DNA.
DR RefSeq; WP_000741335.1; NZ_CP064825.1.
DR AlphaFoldDB; Q1RD15; -.
DR KEGG; eci:UTI89_C1267; -.
DR HOGENOM; CLU_049005_0_1_6; -.
DR Proteomes; UP000001952; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008907; F:integrase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd00800; INT_Lambda_C; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR015094; Integrase_lambda-typ_DNA-bd_N.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF09003; Arm-DNA-bind_1; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}.
FT DOMAIN 84..169
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 191..377
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 380 AA; 43900 MW; 830BE0644996D8C6 CRC64;
MAARPRSHKI SIPNLYCKLD KRTGKVYWQY KHPLSGRFHS LGTDENEAKQ VATEANTIIA
EQRTRQILSV NERLERMKGR RSDITVTEWL DKYISIQEDR LQHNELRPNS YRQKGKPIRL
FREHCGMQHL KDITALDIAE IIDAVKAEGH NRMAQVVRMV LIDVFKEAQH AGHVPPGFNP
AQATKQPRNR VNRQRLSLPE WQAIFDSVSR RQPYLKCGML LALVTGQRLG DICNLKFSDI
WDDMLHITQE KTGSKLAIPL NLKCDALNIT LREVISQCRD AVVSKYLVHY RHTTSQANRG
DQVSANTLTT AFKKAREKCG IKWEQGTAPT FHEQRSLSER LYREQGLDTQ KLLGHKSRKM
TDRYNDDRGK DWIIVDIKTA
//
