ID Q1WMA5_CATRO Unreviewed; 362 AA.
AC Q1WMA5;
DT 02-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 02-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=S-methyltransferase {ECO:0000313|EMBL:AAZ32409.1};
OS Catharanthus roseus (Madagascar periwinkle) (Vinca rosea).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae;
OC Catharanthinae; Catharanthus.
OX NCBI_TaxID=4058 {ECO:0000313|EMBL:AAZ32409.1};
RN [1] {ECO:0000313|EMBL:AAZ32409.1}
RP NUCLEOTIDE SEQUENCE.
RA Schroeder J.;
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAZ32409.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16623883; DOI=10.1111/j.1365-313X.2006.02680.x;
RA Coiner H., Schroder G., Wehinger E., Liu C.-J., Noel J.P., Schwab W.,
RA Schroder J.;
RT "Methylation of sulfhydryl groups: a new function for a family of small
RT molecule plant O-methyltransferases.";
RL Plant J. 46:193-205(2006).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Cation-independent O-methyltransferase family. COMT
CC subfamily. {ECO:0000256|ARBA:ARBA00034481}.
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DR EMBL; DQ084384; AAZ32409.1; -; mRNA.
DR AlphaFoldDB; Q1WMA5; -.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0008172; F:S-methyltransferase activity; IDA:CACAO.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR012967; Plant_MeTrfase_dimerisation.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11746:SF303; F5F19.5 PROTEIN; 1.
DR PANTHER; PTHR11746; O-METHYLTRANSFERASE; 1.
DR Pfam; PF08100; Dimerisation; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 2: Evidence at transcript level;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AAZ32409.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:AAZ32409.1}.
FT DOMAIN 32..83
FT /note="Plant methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08100"
FT DOMAIN 138..343
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 267
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 362 AA; 39996 MW; 636E0F50B998ADB6 CRC64;
MSSHEEKPSS NKEDDDHSSY ALQLVFSGAL PMVLNAVIKL NVFEIIAKAG PGAKLSPSQI
VSQMPTKNPE APVVLDRMLR MLASYSVLTC SVVDFSHGSG QRVYGLSPVS KYFVKNENGG
CFGPLLDLLQ DKVLTDIWYE LAPAVLEGGT AFNRAYNMHI FKYTGINQKF NETFNTATIN
HAKVIVQEIL KNYKGFENLK TLVDVGGGLG VTLDLITSKY PNLKGINYDL PHVTQNAPTY
PGVVHVGGDM FESVPKGDAI FMKWILHDWD DEHCLKLLKN CYKALPENGK VIAVDAILPM
NPDNSSSTKH ISQVDLFTLV LYHPGGKERT ENEFLALVAE AGFGGIRKVC VCCDLWVMEF
YK
//
