ID Q1YXC0_9GAMM Unreviewed; 443 AA.
AC Q1YXC0;
DT 02-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 02-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Guanine-hypoxanthine permease {ECO:0000313|EMBL:EAS40928.1};
GN ORFNames=P3TCK_02236 {ECO:0000313|EMBL:EAS40928.1};
OS Photobacterium profundum 3TCK.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=314280 {ECO:0000313|EMBL:EAS40928.1, ECO:0000313|Proteomes:UP000003789};
RN [1] {ECO:0000313|EMBL:EAS40928.1, ECO:0000313|Proteomes:UP000003789}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3TCK {ECO:0000313|EMBL:EAS40928.1,
RC ECO:0000313|Proteomes:UP000003789};
RA Bartlett D.H., Valle G., Lauro F.M., Vezzi A., Simonato F., Eloe E.,
RA Vitulo N., Stratton T.K., D'angelo M., Ferriera S., Johnson J., Kravitz S.,
RA Beeson K., Sutton G., Rogers Y., Friedman R., Frazier M., Venter J.C.;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAS40928.1}.
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DR EMBL; AAPH01000044; EAS40928.1; -; Genomic_DNA.
DR RefSeq; WP_006228449.1; NZ_CH724134.1.
DR AlphaFoldDB; Q1YXC0; -.
DR HOGENOM; CLU_024508_0_1_6; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000003789; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 443 AA; 47097 MW; EE1EBC485D5BFD53 CRC64;
METVVKKSTF SLAKWFDFQG NKTNLKNEVI GGFTTFATMA YMVAVVPGML SKGGLPFDTA
LTITVLMTVL TTVAMGIYTN RPFVLGPGLG SVAIFSFTLL GNDVPLSIAS GIVFISGVLF
MLVSFLGVRD FIVRIIPHSV KVSVGVGIGL FIALLGFKQA GVIIADPKKN VLIFGDLAAT
NTLVAMLGFF LVLFFVARKI QGGIIIAILL TTLISLPLGI TSIPDSFFSM PGSIDSMFLQ
LDVMGALSPA YLPFLLAFFI PDFFSTLGTL LGVGSQAGYL DKDGNLPGIE KNFHVDSCAT
TFGALFSCPV LTTYVESSAG VEAGGRTGFT AIVTAGCFAL TLFLAPLAGM IPTAATAPVL
MYIGISMMGS MKKVNYDDIT EYLPAFVCVA MSIFSFNAGN GIAAAMLVYA FLKLATGRYK
EDHWSVYVIA ASMIYYFYIV ASH
//
