ID Q21684_CAEEL Unreviewed; 349 AA.
AC Q21684;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 3.
DT 27-MAR-2024, entry version 119.
DE SubName: Full=7TM GPCR serpentine receptor class x (Srx) domain-containing protein {ECO:0000313|EMBL:CCD65672.1};
GN Name=srx-3 {ECO:0000313|EMBL:CCD65672.1,
GN ECO:0000313|WormBase:R03H4.3};
GN ORFNames=CELE_R03H4.3 {ECO:0000313|EMBL:CCD65672.1}, R03H4.3
GN {ECO:0000313|WormBase:R03H4.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD65672.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD65672.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD65672.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX284605; CCD65672.1; -; Genomic_DNA.
DR PIR; T28861; T28861.
DR RefSeq; NP_505329.2; NM_072928.3.
DR AlphaFoldDB; Q21684; -.
DR SMR; Q21684; -.
DR STRING; 6239.R03H4.3.1; -.
DR PaxDb; 6239-R03H4-3; -.
DR EnsemblMetazoa; R03H4.3.1; R03H4.3.1; WBGene00005894.
DR GeneID; 187549; -.
DR KEGG; cel:CELE_R03H4.3; -.
DR UCSC; R03H4.3; c. elegans.
DR AGR; WB:WBGene00005894; -.
DR WormBase; R03H4.3; CE36394; WBGene00005894; srx-3.
DR eggNOG; ENOG502TFQT; Eukaryota.
DR GeneTree; ENSGT00970000195873; -.
DR HOGENOM; CLU_059457_0_0_1; -.
DR InParanoid; Q21684; -.
DR OMA; FLFDQEY; -.
DR OrthoDB; 2881924at2759; -.
DR PhylomeDB; Q21684; -.
DR Proteomes; UP000001940; Chromosome V.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR019430; 7TM_GPCR_serpentine_rcpt_Srx.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR PANTHER; PTHR22718:SF22; 7TM_GPCR_SRX DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR22718; SERPENTINE RECEPTOR, CLASS X; 1.
DR Pfam; PF10328; 7TM_GPCR_Srx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:CCD65672.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..276
FT /note="7TM GPCR serpentine receptor class x (Srx)"
FT /evidence="ECO:0000259|Pfam:PF10328"
SQ SEQUENCE 349 AA; 40151 MW; CE1481E542181FD0 CRC64;
MGVSLKQSLG FFIGLLSGTS LILNVLALIA VFRLAFIVRK NHVYIITFFN ILSNVIQMAL
ATFYLAPTII TSSFLVSTEK KSKWTLVFGS AFLFFWYFET FTQIVMALNR YLVICLQKHH
IFTTTTTILI FLFLIPFSFG LMYNSQYVNP CCSFLFDQEY LSYSYYTLDG VTNYSDEFDI
PLNASSSIIS GLCYIKIFWT QHKSSPICPT FAAEQLKRRR KKDIRYAIQF SLTLVFYIFV
WVFLRVLPVM LENRHVEWFI LVPFFYTVNC SSAAIINIGL NNEVQKNLLP KSIYPLLQHF
GLTRFDAPTI NATLASVTIQ SKPSVLPVAI RFIPTNQHQP FRSIGVIRD
//
