ID   Q21G77_SACD2            Unreviewed;       878 AA.
AC   Q21G77;
DT   18-APR-2006, integrated into UniProtKB/TrEMBL.
DT   18-APR-2006, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ABD82302.1};
GN   OrderedLocusNames=Sde_3045 {ECO:0000313|EMBL:ABD82302.1};
OS   Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC   Cellvibrionaceae; Saccharophagus.
OX   NCBI_TaxID=203122 {ECO:0000313|EMBL:ABD82302.1, ECO:0000313|Proteomes:UP000001947};
RN   [1] {ECO:0000313|EMBL:ABD82302.1, ECO:0000313|Proteomes:UP000001947}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2-40 / ATCC 43961 / DSM 17024
RC   {ECO:0000313|Proteomes:UP000001947};
RX   PubMed=18516288; DOI=10.1371/journal.pgen.1000087;
RA   Weiner R.M., Taylor L.E.II., Henrissat B., Hauser L., Land M.,
RA   Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H.,
RA   Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R.,
RA   Richardson P.M., Borovok I., Hutcheson S.;
RT   "Complete genome sequence of the complex carbohydrate-degrading marine
RT   bacterium, Saccharophagus degradans strain 2-40 T.";
RL   PLoS Genet. 4:E1000087-E1000087(2008).
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DR   EMBL; CP000282; ABD82302.1; -; Genomic_DNA.
DR   RefSeq; WP_011469518.1; NC_007912.1.
DR   AlphaFoldDB; Q21G77; -.
DR   STRING; 203122.Sde_3045; -.
DR   KEGG; sde:Sde_3045; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_6; -.
DR   OrthoDB; 6168558at2; -.
DR   Proteomes; UP000001947; Chromosome.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001947}.
FT   DOMAIN          184..238
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          311..381
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          384..436
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          467..601
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          610..866
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   878 AA;  98865 MW;  02B3583D84BB360A CRC64;
     MLLDRRQDVE LRDAVSSLRQ MLSVAKDAST AYQDTLKTAC ELTHSPFGFI AKREIIDGSL
     ELKVSHLCHN EVEATSVSEP LFLPLTPQVK LNFCNGAQLI SQQDLTKLQG FFEGVERFKQ
     MMAIPISDAH SIHGVLFLAN AQTAYHTSLS MRLWPLITNC ICIARIIDQR KNSTDQSPPQ
     DSSTPNELYY LFEGVCPLSV VTVDHQLKIV RMNPRAEAIF GYNQNQIIGS HISTLLPERF
     TNEHHTQTFA YNPLAPPQHT SSPMIGRSYK GVAINFDVNK LQYVLKGKRH HILIMRDTTE
     IEIARAQHED EVERFRILAD LAPVGILQAN SDWSGIYAND RWCEIAGRSM SDILELGWLS
     AIHPDHFHNV IEPLRTAISE GKEFKRECLF LKPNSEQTWV ELHARPQIST NGDITGFIAT
     ILDSTFRHEA EDKLRELAEH DPLTGLANRA MFQHRLEHGL SRTHRHGSLA LLCLDLDGFK
     NVNDTLGHDS GDELLIEVAK RLTKCVREED TVARVGGDEF MILLEGLKDA QIAAEVSEKI
     LNSLEPPCSI NRQEVFISTS IGITFATKGD KNDSKSLMKQ ADMALYRAKH EGRNNYQYYS
     PDLERASQER LYLGNSLHHA LQRTEFQVFY QFKSSLSTHK VTGFEAVLRW EHPRRGQLQP
     DQFIPILDES GLIVPVSRWL THTSFMQHAK WKAKGLIEKD AKIAVNVSPR LLRDPYFIRG
     LANSIQDSKI DPTSVIIEIT ETALLEHSEQ TTDALNGLKR IGVAISLDDF GTGFSSLTHL
     KRYPIDQIKI DRSFVQNLLK DSGDKAIVKA VIVLAKSLKL TVVAEGVEDK ATLDYLASLN
     CDEYQGFYLN KPQPAEEIEN LLLNGLQLAP SQADNSSK
//