ID Q22G03_TETTS Unreviewed; 994 AA.
AC Q22G03;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 22-FEB-2023, entry version 49.
DE SubName: Full=von willebrand factor type A domain protein {ECO:0000313|EMBL:EAR84223.1};
GN ORFNames=TTHERM_00721540 {ECO:0000313|EMBL:EAR84223.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR84223.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662576; EAR84223.1; -; Genomic_DNA.
DR RefSeq; XP_001031886.1; XM_001031886.1.
DR AlphaFoldDB; Q22G03; -.
DR EnsemblProtists; EAR84223; EAR84223; TTHERM_00721540.
DR GeneID; 7838104; -.
DR KEGG; tet:TTHERM_00721540; -.
DR eggNOG; ENOG502RRKH; Eukaryota.
DR HOGENOM; CLU_301012_0_0_1; -.
DR InParanoid; Q22G03; -.
DR OMA; ADIMDEN; -.
DR OrthoDB; 1379584at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 46..230
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 994 AA; 115403 MW; 4F9E526E2B00579D CRC64;
METQQSVQAK AQFKVESFEG NEFIDFTLKL KLDETALVQN NSRQKNYQIV IDNSGSMDGT
NIQLTKQLCN ELVQFVIKTQ PHSKISLMTF NTSIDHVENL HLKSLKQVEQ FISNINANGG
TIFHITFDKL RDICQKFTNQ NEELVIVYLT DGQVQSGQDS TNLKDSFIFL QQVLKKFVNN
VEVHALGMGT SHDPVILDKI ISLQTTQSTY QFIKESSEIE GAFKNIVDII GQNFIEAYLQ
RKDGQLCRIP LLKSAIDVSQ KQKNCVLIDN DLKEKIFYNS KTKDLVQELE SNFQLIINLN
HTTNIEIPHH IKDKRISKMS EGDSKQLFEQ INQMYNYLET KLKLIIQELK EYVNQKRTSI
EKEQIVKFSN QINQINSAYS SSISKLFKLS SLQRQKINEN NPTLSTRIKE AVDIVSKLST
STISTIEIAL LNQLAYPTIT NRLFAKRLEK RKGASIQQFN DYEILKEKYL QEFQSKEQQL
SKDLSQLSQE IGVCFLSCQD ITESILNKDC LCVTFSVTRS ELAIVRPESL KIKAVQPSII
SAKSFIDCIK YSLDISLENS GSFNKQQGNI VQGMMREVIN AAMPLYIHKE HWNMAKLWLE
PILGWVVTLD PLGYHHAQKR TIPFMLLNHT IRQLIEYGIT KYGLKQIDLI FQTCSQIIKE
EEQDSVQLQI ENSQALKIRE EIIKQYEGFM QDASQRLGEK ITNIEIFLAK LYIAKTLDWI
QIKKDDIKTF FRYVIEEQLR RNMSEYYLKF PILSLIQLFD GNNVVFTNMN NEFLNNLSST
LSIVHYYRFL FEGFNEQDSI NKSINITQSK IDMITLVMAD NIDQVKALFA QNTIQGQDKV
RRSSIGLKKY FDPYSQEYNV LDAIKEIQKQ EQVNKVSYVE EMASKSKHKL NIKGQFYFTC
PDISKKLQDQ MDQLAENDNI NDFKIQLEQM SQYKQDRQWY LWYLISKQVD QLKEKLLVVK
EKFGPFKKFK KYQIYCLTKG GYLNSSDITE LETP
//
