GenomeNet

Database: UniProt
Entry: Q23DY9_TETTS
LinkDB: Q23DY9_TETTS
Original site: Q23DY9_TETTS 
ID   Q23DY9_TETTS            Unreviewed;      3315 AA.
AC   Q23DY9;
DT   18-APR-2006, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 2.
DT   05-JUL-2017, entry version 72.
DE   SubName: Full=Cation channel family protein {ECO:0000313|EMBL:EAR94798.2};
GN   ORFNames=TTHERM_00675710 {ECO:0000313|EMBL:EAR94798.2};
OS   Tetrahymena thermophila (strain SB210).
OC   Eukaryota; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR94798.2, ECO:0000313|Proteomes:UP000009168};
RN   [1] {ECO:0000313|Proteomes:UP000009168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX   PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA   Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA   Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA   Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA   Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M.,
RA   Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E.,
RA   Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K.,
RA   Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C.,
RA   Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M.,
RA   Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C.,
RA   Barbeau R.A., Hamilton E.P., Orias E.;
RT   "Macronuclear genome sequence of the ciliate Tetrahymena thermophila,
RT   a model eukaryote.";
RL   PLoS Biol. 4:1620-1642(2006).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; GG662711; EAR94798.2; -; Genomic_DNA.
DR   RefSeq; XP_001015043.2; XM_001015043.2.
DR   STRING; 5911.EAR94798; -.
DR   EnsemblProtists; EAR94798; EAR94798; TTHERM_00675710.
DR   GeneID; 7826435; -.
DR   KEGG; tet:TTHERM_00675710; -.
DR   InParanoid; Q23DY9; -.
DR   Proteomes; UP000009168; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005261; F:cation channel activity; IBA:GO_Central.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000009168};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    201    219       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    231    256       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    268    293       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    443    469       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1695   1717       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1729   1750       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1757   1775       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1823   1845       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1898   1923       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2155   2176       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2234   2263       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2350   2377       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2433   2452       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2472   2491       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2498   2516       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2557   2588       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2637   2660       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      199    472       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1695   1927       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     2117   2373       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     2433   2665       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       72     99       {ECO:0000256|SAM:Coils}.
FT   COILED      890    917       {ECO:0000256|SAM:Coils}.
FT   COILED     2973   3000       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   3315 AA;  384308 MW;  0A7979A41B448E37 CRC64;
     MKQSTENNQN DEHGQQKSSK WIQKLKTIFE NELPSSSKKK QKIKDKKVIL QTQDSQTDDY
     EENSDDVNSQ DMSFLQNKKD KKKEQLKFLY EQIAAEMNQK DDGNNHDEED LWDWMRNQNK
     YEEKDSDEQL IHSFQEQEAE FLALKEKEEQ NKFLDIVEMN EYQKIQKFNA DTLPRKIFKQ
     IWSIKNAISQ ICNIIINSKP FEYATLCVIL FNCVILAMDD PTTNADDQQR LQIDLILLIL
     YTVEMGFKIL ALGFIFNKGS YMRDMWNILD ITIIITGYLP YVVNTSQVNL SAVRSLRVLR
     PLRTISRIKA LKQILNTLFS SFSLLKDAII IIIFFYLVFA IAGQQLFTGC LKKRCFDSSN
     GIQFGDNDQN VFLCIEDIDC YQYAESNSKI HYICGKGMVS PFWDTENFDT FGWALLNVYV
     VVSQEGWSTI QAQVQQTFGY PSFIYFMICV LVGNMFLENL LMAIIQIKYE ESERLLKKRQ
     KAIEDVQSFN LADFIRWGIY KSNKQVYKEL EEKKIKKVST LSEIISFFKQ GAQIKKLFTI
     TKSKSNSGSP NNKDKQIEEN IHNFKSIEEL ENQSADKNQA EKLGKEQKVQ QQPANLGTQF
     EQSKPLIEQE LQEIHDQNLN TFKSQETNLN LLLKIPMIGL KESQLSVFNN YNSNFSPTYS
     VAHFSHNIKQ NQELANFTYE DQNLNLNKLQ KSIHIKDLDQ MANNQQSQFP KFNPIMKRQP
     QYLKKSSIRE KSPKRGYQRK NSRKMTTKKT MIIKPLEGTQ TQIRNSVSNN NNTQIRLTVA
     KNMNSSHQSR NPSEIHQNSQ LNQTNFQRDK SVNQNTYISN NTYHQGSNQQ TIMLQPSVIL
     KSKQNRNSNV LNILNSQIIP ARKVESDEGS SIDSHQNKDF DEEEQFFKEI EKTYEINQKL
     NRQLELKETE DNQYIENIIK DRQIERNYRQ KTVTLDNLIN NQINKQPLHH DQLSLSSIQE
     SYQKDTPEEQ NLMFQSIQKR SFKKKREVSI QGQLQSSEIS RPYDPESPKK AMSSKRIKQL
     PNIPSASLNT SSKIQKSSHV SIILENSLNN SKQKQIRSAS QTDFKVDSKQ SILEQRKNSY
     FYDGLFSDED FDNVKQFRKQ ISKKTSIASK TGNNKNKKEL QKKKSVKDKN VVDENPKVSI
     INQVLSKDEG QLYRKLFLKK DVIARVLYKE PTNYDDDILP KEKLIKKEKK KQDRLDKLKK
     MKFSISYQAE KRVKLRSQVV EEKKKKMEKM KFLPIKANRT ALALIHQQPQ VYPGGVNPLD
     LAAAQNKIKS QTLIGQQNTQ KNNHENMSQG TYNRAPSIVQ QLLKQQTLIL QKGKIDDEKV
     RLQGDASQKN NLIPQSALSL EYFENQEKIK KGLNLIIPDS DKNSQSNTGS QQVIEANLIQ
     KKGTLGNNDQ SDQLLKANLT PKTAKGILKI KSITGNENSN LNTELNRSQT NKQLDESLLN
     KKKTSGYTGN TGRHQGDNPA FEWDLIKARE MLFPTDHEEE EKSQRESEFS QVFGDNASIF
     NSILDESKSK NSFNSSSFHQ SYGTSSKFES SSMNSYSMKS QSKEGKSAFD ETNADTASKR
     SKYSKNKDDT NSKAQDSNKS KDGKEDKGNG ENQDYFQKPQ TLEQFLKEPL EKEYVQVVKQ
     QVNNLIQKGQ NKIKSYWSGD DVLVATKVYK QQQAIKTLMK CLNYPNTITE QNEGGFMGIV
     NAFRRRVRML VQTPLYENLI MIAVVMNTVI LSLDGSVDNQ SILDQFNQAF TYIFAIDMGL
     KLIGLGFALY CADRMNIFDG LIVILSIFDI IFLSGSSGGS SFSAFRSLRI LRVFRVLRVT
     RLLRSLKFMK ILIKVISSIL DKLFYIILLL ILYIFIYTLI GMQLYGGSFL SVSRSNRMVF
     DSFLQASFSV YDLLTIENWN NILYVALRTQ VNVGITCIYL ISCIFIGNFI IMNLVLATMI
     GAFNSSQFDK EKEEIANTVE IVEDLDLGHT TTLNSTTFMN MSNSQSRLGS STHSFSVKNR
     QRMLSSGGSS QGYSDEHSQN NHSQHSFSKK SQQIQKESFS REYKEKASSI SDSHNQSLDN
     KSSHNLELQI VSEQEQNNDK NNQKNMFKQQ AVVKKDEDDE KEEIFLFFDN IKCQKSLYIF
     SMQNKIRRAF YFIVKNPLFD NIILAGIILN SVKLVSDTYD TGSDSQKQAS QILDIMFTVF
     FSIESCLKIV SYGFFFDENS YLRDNWSKLD FFVVVTSIID VSLQNGNFAS LKILRLLRTL
     RPLRVLHHNK SMKLIVTTLL ESIVGILNML LVIFLVWLMF AILGVSLMGG KLQYCNFPNN
     GISYNIYKYN QSQCSRVGGS WQTYDLNFDN VPAALLNLFV ISTFEGWPAY VFNYLDGSSD
     GPVYFGSAYF SIYIVFFILV GSFFSIDLFG AVLSFHYDIA LQKSKNKYLS SEQTQWIELQ
     RLILQSKPDY NSISLPTNKF RKFIWNICES QKLEIFIMIC IIGNIVSMAL SYDTSPSSYD
     TILQDINLGF SIVFITECLL KLIAYGFNGY FYKSSNQFDF FVVSVSVIDI IFTYSGNQFI
     KFLSAGPQIA RIFRVFRVTR LLRLIKQFEG LQKLMSTLIY ALPSLTNATA LLFLIYFIFA
     ILACYLYSPY QTGNSLNSFQ NFSTFHRSYL LLFRMSTGED WYLIMFDIIH HTNMWSAFFF
     VVFIIIQQYI MMSLFILIII EQFENNYINP DNPINDFQYS EEDFKKQWVQ FTRNSYGIKI
     HERFITDFYF SILRPLGFDY KSKLKEFVEQ VKTINQQVSE QDLELITGKF RIKQKQLAEK
     EIMKMNIRCD YDGYIFYNEL LYYFFKHSLY DSVFGRIDNA STKSEYEKCI KAEEILYKEE
     HITRRKLRIL KKKQAALTKQ KFISSRQKEV NPMVRRLFVG MCFKSWLKYS QKIQNNIMQD
     YDDISSQTDS DEEYDQLQVD PEDLQNALAI DKFYTSQDKE ENIIEVLKNR RFIIPRLHTI
     KLRKQDQKEQ IADGFFNGKY FEFPNPDEIY KAELENEQNI NEFEERINEQ QKQLQIIKNN
     EQNNKQMLSS VNSNYQERTK SIQRSQLNNQ RNNTLKLSHA FNIPSKRTSI DVNNLNLIHS
     NNLLSIQNVQ SNNQLVPKDQ TKLKLSLVES SNSLGMSVRK ESIVKKDSHN VSTPKSQLNL
     SQVKKLTLQK NNSNSPRLQV PLENNRQRKD SKSIFSMTPQ NRANENENIE DKLNSQHLMH
     LQATPITFTQ FVNSKNFMSS PENESDDEHK QQIRLDLTKQ QSSQIKSPKK EISRFGESSS
     IINQLKQDFN INGHEKNNES NDKHSSIMNM PNLQQKSYSQ QSDKHQAKIP IDNQEHKKPN
     LNKNIPQIRI NFEED
//
DBGET integrated database retrieval system