ID Q23JA1_TETTS Unreviewed; 442 AA.
AC Q23JA1;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 24-JAN-2024, entry version 70.
DE SubName: Full=BRCA1 carboxy-terminus (BRCT) domain protein {ECO:0000313|EMBL:EAR96603.2};
GN ORFNames=TTHERM_00490710 {ECO:0000313|EMBL:EAR96603.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR96603.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662691; EAR96603.2; -; Genomic_DNA.
DR RefSeq; XP_001016848.2; XM_001016848.2.
DR AlphaFoldDB; Q23JA1; -.
DR STRING; 312017.Q23JA1; -.
DR EnsemblProtists; EAR96603; EAR96603; TTHERM_00490710.
DR GeneID; 7836882; -.
DR KEGG; tet:TTHERM_00490710; -.
DR eggNOG; ENOG502RT34; Eukaryota.
DR HOGENOM; CLU_558396_0_0_1; -.
DR InParanoid; Q23JA1; -.
DR OrthoDB; 19990at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR CDD; cd17744; BRCT_MDC1_rpt1; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR PANTHER; PTHR47667; REGULATOR OF TY1 TRANSPOSITION PROTEIN 107; 1.
DR PANTHER; PTHR47667:SF1; REGULATOR OF TY1 TRANSPOSITION PROTEIN 107; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF16770; RTT107_BRCT_5; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR PROSITE; PS50172; BRCT; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 263..316
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 350..442
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 126..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..180
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 50949 MW; A79D3875FC39FDFE CRC64;
MKSFDLVLVT GNKASDKQIF QMLSGKNVIG TNIKCTTQIE QKLIKPMHFE LLINKSGRIT
IIPLTSGMQI MQKNKKLKEL DVNQCYDLEI KQSFYIERTY ACYLEEAVTK KSPIQPSQQG
KQSIWNLKNN AQNNEDKNKK KLKKEAMDID SQVLSESTQS KSDEIDDLAD EDYDNQEEQE
EIVKDEIKRR KAPSNSSKNS VSKKIKSPNS CETTTIMQAE KKIEVEEQKT NTKQNNNNKQ
KKQVRVILSN CNLTNAEKNK MIKLGAVFVE NQEEDFDVVV MEEFRRRAKL LIGLNKKAWI
VSKGWILDCI DDDELITDFC EYLIEVPLED QKKYNNLNLD NVQYNIQKGK GFKLFENCSF
FLQGQYKNIL IDELQAIIIS GGGKIINNLN HSFSSDKQKQ IAVIEDPKKI KNPLNNTLYV
DPEYILLSTL KQQIQTKCIY NI
//
