ID Q23TZ4_TETTS Unreviewed; 731 AA.
AC Q23TZ4;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 24-JAN-2024, entry version 74.
DE SubName: Full=EF hand protein {ECO:0000313|EMBL:EAR99987.2};
GN ORFNames=TTHERM_00961930 {ECO:0000313|EMBL:EAR99987.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR99987.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662632; EAR99987.2; -; Genomic_DNA.
DR RefSeq; XP_001020232.2; XM_001020232.2.
DR AlphaFoldDB; Q23TZ4; -.
DR STRING; 312017.Q23TZ4; -.
DR EnsemblProtists; EAR99987; EAR99987; TTHERM_00961930.
DR GeneID; 7828960; -.
DR KEGG; tet:TTHERM_00961930; -.
DR eggNOG; ENOG502SQPK; Eukaryota.
DR HOGENOM; CLU_253561_0_0_1; -.
DR InParanoid; Q23TZ4; -.
DR OrthoDB; 22466at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 61..96
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 97..132
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 268..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 598..656
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 731 AA; 85374 MW; 16914C50AA4CC854 CRC64;
MSNQTQQDDN EYVFENLNEY QAFVKNNKRT KLHNKSTVSW LKTRYSNKTK KHYLLFPEEL
IEDMKIRKIF KIFDKDGSQA LDLKEMVEMF QKYNIEIDKE ELQQIYNIVD KTKDNALNYL
EFKECAISQD ANAIFSKMIS KVRTQEQQKK SAEERNIYLP QRFSEMVTYL SYRINREDLE
DYLRERNHRI SERYEKYLQL MNLNGLDSAG ATAHENQIKD QKKLDKASDL EQKIFDRQSS
SDSDGESLEA EKSFRNQIKE EQLKKQQKAQ YRLSQATNSV NRSQPHLMST SPRHGSLQIE
LQAQNSNYFL QSSVAGAQTY GTQGSNYNNS NSQLAASRGS IRNSKIRTQG KKEMDEEQIH
NKFTKYEAQS LSKKAQLKGK DDAQNLYTEV SKQYGTQENF YKTFQSTQNW QNANNDTQAG
LKNKTQLQTD ETDSQLGSVE NKKSAERSNL LPLSTTFQNH RGGIGKFFGS NGQDFESTQN
SQNINNNIYG TRQKYSNDDF RHTDFKGFNN KSHNQLGTMR SVSQFMTSKN KFNSTFYTLG
KRPTTNQSQL KTLGIDKSSF KSICNIMNKT LLQLENKKIT NNLFIKTAPS STRFSYNKQN
QENKVQNMSQ KLLNQNIENN IIDPKLMQSI YKPNQIQEYQ EREKQLINEI KQDIMNKFLM
NNQVAVSLFE DLQKSNQKPY YKVNHSITTE QSFLKQNRLP ELDMMNKVYE KDKTPIGKHM
NNQLDSKYLK N
//
