ID Q245V8_TETTS Unreviewed; 376 AA.
AC Q245V8;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Heterochromatin protein {ECO:0000313|EMBL:EAS03525.1};
GN ORFNames=TTHERM_00245410 {ECO:0000313|EMBL:EAS03525.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS03525.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662474; EAS03525.1; -; Genomic_DNA.
DR RefSeq; XP_001023770.1; XM_001023770.3.
DR AlphaFoldDB; Q245V8; -.
DR STRING; 312017.Q245V8; -.
DR EnsemblProtists; EAS03525; EAS03525; TTHERM_00245410.
DR GeneID; 7827421; -.
DR KEGG; tet:TTHERM_00245410; -.
DR eggNOG; ENOG502SBNR; Eukaryota.
DR HOGENOM; CLU_736698_0_0_1; -.
DR InParanoid; Q245V8; -.
DR OMA; SEMWENE; -.
DR OrthoDB; 181038at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR CDD; cd00024; CD_CSD; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR Pfam; PF00385; Chromo; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS50013; CHROMO_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 53..110
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 103..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 44196 MW; C10C1A45FD9BF9BF CRC64;
MSDTTTTANS KKNTKINGKQ QGSKDKAEKK EKAINKKKYE SEDEEEEEEE EFYIVEKILD
YKKIKNRDLF LVKWEGYEEL TWEPKSNLSN VKQLVENFLK TLKDKGKKEN SENLESSSAL
QEGSESKKQQ LSGGKIQKKE VKSPISISKE KQAEKVKQDE GSHLKRDVED HHNISISSMK
GKKDDDGEQN EEQENKVVVK QEDVDEEKQS TKKRGEEEEE QQQQQNSKQI EEEEEGKDVQ
KEKKQQNEEK QDIKHLEQKE SKEDHDAIQQ QQKNTSLNKK RKKEEQSQDD IDEQNEQDKP
QDKVKHLPEI LGNLEEHIPL EISKAVYKTS KFQYLVQWKQ QQGIKIIPSF IFSDDLLKRY
SDLIVHFYED KALKRK
//
