ID Q24S22_DESHY Unreviewed; 596 AA.
AC Q24S22;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=DSY3381 {ECO:0000313|EMBL:BAE85170.1};
OS Desulfitobacterium hafniense (strain Y51).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfitobacterium.
OX NCBI_TaxID=138119 {ECO:0000313|EMBL:BAE85170.1, ECO:0000313|Proteomes:UP000001946};
RN [1] {ECO:0000313|EMBL:BAE85170.1, ECO:0000313|Proteomes:UP000001946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y51 {ECO:0000313|EMBL:BAE85170.1,
RC ECO:0000313|Proteomes:UP000001946};
RX PubMed=16513756; DOI=10.1128/JB.188.6.2262-2274.2006;
RA Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K.,
RA Inatomi K., Furukawa K., Inui M., Yukawa H.;
RT "Complete genome sequence of the dehalorespiring bacterium
RT Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides
RT ethenogenes 195.";
RL J. Bacteriol. 188:2262-2274(2006).
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DR EMBL; AP008230; BAE85170.1; -; Genomic_DNA.
DR RefSeq; WP_005815777.1; NC_007907.1.
DR AlphaFoldDB; Q24S22; -.
DR STRING; 138119.DSY3381; -.
DR KEGG; dsy:DSY3381; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_9; -.
DR Proteomes; UP000001946; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000001946}.
FT DOMAIN 31..101
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 188..321
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 330..584
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 596 AA; 67698 MW; 5B3E0C01DE0E2430 CRC64;
MRKSSILARN KTIAKNEKKH NPGESYALKN LQRRFQVLVQ DSHDVFEIIN SDGTIQYISP
AVEKILGYKP EERIGKPAYE LLEPTEKYKF KQMLSLAFNH PDQVVQEEIK IKTKAGQEII
LSCDMRNKLS EPSIQGVILN WRVSSSDRNR EDSQAKAPAT LDELTRLPAR GAFESLLSQH
MAEARGEEAL ALIIVDIDRF KYINSYLGYE HGDQLLRQIS RRLRLLCTDQ VLLCRFSGDQ
YAIVAARGEG QDDYLPLVEE VLRLFDAPFI VDEHKLDISV SLGISLYPHD AQDSETLVKS
AYAALLRGKA AGKKHYQFYS ADVEHKNYRE FLLRRDMQKA LKEGQFAVHY QPIVNLYTNE
VLAVEALLRW KHPLCGMISP AEFIPIMEET GFIVDMGKWL LEEVCRSHKQ WQKEGLPPLK
VSINCSSVQF AEECFVESIQ AILDKMQLDP RYLIIEITES VLIDNAKKVI ADLQKLQEIG
ILVAVDDFGT GFSSLSYLLT FNIDIIKIDS SFIQNIPTNK TSTIITHSVI NLARELNIKL
VAEGIESPEQ LSHLKRFNCH TGQGYLYSKP IPQHQLAEII ANKKCEPQIN AEALGI
//
