ID Q259Q3_ORYSA Unreviewed; 1827 AA.
AC Q259Q3;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN Name=H0818H01.16 {ECO:0000313|EMBL:CAJ86094.1};
OS Oryza sativa (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=4530 {ECO:0000313|EMBL:CAJ86094.1};
RN [1] {ECO:0000313|EMBL:CAJ86094.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2] {ECO:0000313|EMBL:CAJ86094.1}
RP NUCLEOTIDE SEQUENCE.
RA Han B.;
RT "Chromosome-wide comparison between domesticated rice subspecies indica and
RT japonica.";
RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AL732346; CAJ86094.1; -; Genomic_DNA.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR005162; Retrotrans_gag_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR37984:SF10; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF03732; Retrotrans_gag; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 2.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 1539..1701
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 1..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1054..1188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..143
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1154..1188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1827 AA; 201133 MW; 62C7CF449C0BCE13 CRC64;
MAEQAKAHDL SPSMSGDDGE LNPRRRARTP PPPPRQSPRR EKALERAEGS ATSTSTGGGE
GRRDGERRLL VYGDGSTPQG ALQAAGALLR HPPVAHDPES PAQRWLDDVA KLVMTARQRL
DAGGRSSATK ASGAATTGSA SSRRRARRAA AAVRHSAATP SSTPLTREDL RGGPDARISI
ERRRNGRRAP HATEGASSSG VSPHHRRGDQ PSVPPVGGVG CRAFVASLRN VRWPPRFRPT
IAEKYDGSVN PAEFLQVYTT GIEAAGGDDR VMANFFPMAL KGQARGWLMN LPPASVHSWE
DLCQQFTMNF QGTYPRPGEE ADLHAVQRRD DESLRSYIQR FCQVRNTIPC IPAHTVIYAF
RGGVRHNRML EKIASKEPQT TAELFQLADR VARKEEAWTW NPSGSGVAAS AAPGSAAQTG
RRDRRRKKRS AHTDDEGHVL AVEDASRATR KGRPAGDKKK EAGAPSRERP TDKWCIVHNT
SLHDLADCRA VKSLAERTRK WEEERRQERR EGKSPAVPSS NRRSEAKQKA PAEDIDDSDD
DLGFQEPGAT IATVDGGECA HVSRRSLKAM KRELLAAAPT HEATRRARWS EVALTFDQTD
HPPCVARGGQ IAMVVSPTVC NVKLGRVLID GGAALNILSP AAFDAIKAPG MVLRPSQPII
GVTPGHTWPL GHIDLPVTFG GPANFRTEQV NFDVADLSLP YNAVLGRPAL VKFMAAVHYA
YLQMKMPGPD GPISVHGDLK VTLACMEQRA DRLAVASKPE GGDERLGTSA PAAPRQRIVT
CDEVPEDALV SFLRANADVF AWRPADMPGV PREVIEHRLA VRPGVRPVRQ KVRRQAPERQ
AFIREEVARL LEAGFIREVI HPEWLANPVV VPKANGKLRM CIDYTDLNKA CPKDPYPLPR
IDQIVDSTAG CDLLCFLDAY SGYQQIRMAR EDEEKTAFIT PIGTYCYTTM PFGLKNAGPT
FQRTTRISLG SQIGRNVEAY VDDLVVKTRN QETLLSDLAE TFESLRSARI KLNPDKCVFG
VPAGKLLGFL VSARGIEANP EKIRAIERMR PPASLGMCNA SPTVPGAPEP QDGLRATAGR
PHLSPSDPEA NPVPARLGRE QGEETPEPNG GLRPLTTGVG PLPACPTTPG ASDPQDGPGA
TVGRPPLSSS DPEVVGTEDE RASRGRLDEE RPRDVAPSEG DRPHRKVQRP VYFVSKALRD
AKTRYPQAQK MLYAILMASR KLRHYFQAHR VMVVTSYPLG QILHNREGTG RVVKWAIELS
EFDLHFEPRH AIKSQALADF VAEWTPTPEP VSVPEASSGP SQLPHTAHWV MQFDGSLSLQ
GASAGVTLTS PSGDVLRYLV RLDFRATNNM AEYEGLLARL RVAAGLGIRR LLVLGDSQLV
VNQVWETDAP DRPPMPVGVQ ASGPEGSAPS SLRLIAWIAE IQAYLTDKTL PEDREGSERV
RRISKRYVLV EGTLYRRAAN GILLKCIPRE QGVELLADIH EGECGAHSAS RTLVGKAFQQ
GFYWPTALND AVDLVRRCRA CQFHAKQIHQ PAQALQIIPL SWPFAVWGLD ILGPFRRAPG
GFEYLYVAID KFTKWPEAYP VVKIDKHSAL KFIKGITARF GVPNRIITDN GTQFTSELFG
DYCEDMGIKL CFASPAHPRS NGQVERANAE ILRGLKTKTF NILKKHGDSW IEELPAVLWA
SRTTPSRATG ETPFFLVYGA EAVLPSELTL RSPRATMYCE ADQDQLRRDD LDYLEERRRR
AALRAARYQQ SLRRYHQRHV RARSLCVDDL VLRRVQTRAG LSKLSPMWEG PYRVIGVPRP
GSVRLATSDG AELPNPWNIE YLRRFYP
//
