ID Q28ES2_XENTR Unreviewed; 460 AA.
AC Q28ES2;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 07-JUN-2017, entry version 80.
DE SubName: Full=Novel protein similar to interferon regulatory factor transcription factor {ECO:0000313|EMBL:CAJ81559.1};
GN Name=irf6.2 {ECO:0000313|Ensembl:ENSXETP00000040399};
GN ORFNames=TGas087d13.1-001 {ECO:0000313|EMBL:CAJ81559.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC Silurana.
OX NCBI_TaxID=8364;
RN [1] {ECO:0000313|EMBL:CAJ81559.1}
RP NUCLEOTIDE SEQUENCE.
RA Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
RA Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
RA McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G.,
RA Voigt J., Zorn A.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSXETP00000040399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
RA Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
RA Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
RA Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
RA Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
RA Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
RA Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
RA Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
RA Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [3] {ECO:0000313|Ensembl:ENSXETP00000040399}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IRF family. {ECO:0000256|PROSITE-
CC ProRule:PRU00840}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00840}.
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DR EMBL; AAMC01081469; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CR848098; CAJ81559.1; -; mRNA.
DR RefSeq; XP_012818525.1; XM_012963071.2.
DR RefSeq; XP_017949408.1; XM_018093919.1.
DR UniGene; Str.77451; -.
DR STRING; 8364.ENSXETP00000040399; -.
DR Ensembl; ENSXETT00000040399; ENSXETP00000040399; ENSXETG00000018661.
DR GeneID; 594951; -.
DR CTD; 594951; -.
DR Xenbase; XB-GENE-5910331; irf6.2.
DR eggNOG; ENOG410IFCV; Eukaryota.
DR eggNOG; ENOG410XRXT; LUCA.
DR GeneTree; ENSGT00760000119093; -.
DR HOGENOM; HOG000037433; -.
DR HOVERGEN; HBG105715; -.
DR OMA; WAVETSK; -.
DR OrthoDB; EOG091G067P; -.
DR TreeFam; TF328512; -.
DR Proteomes; UP000008143; Unassembled WGS sequence.
DR Bgee; ENSXETG00000018661; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD_dom-like.
DR InterPro; IPR008984; SMAD_FHA_domain.
DR InterPro; IPR011991; WHTH_DNA-bd_dom.
DR PANTHER; PTHR11949; PTHR11949; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF49879; SSF49879; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 2: Evidence at transcript level;
KW Complete proteome {ECO:0000313|Proteomes:UP000008143};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00840};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00840};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Transcription {ECO:0000256|PROSITE-ProRule:PRU00840};
KW Transcription regulation {ECO:0000256|PROSITE-ProRule:PRU00840}.
FT DOMAIN 7 115 IRF tryptophan pentad repeat DNA-binding.
FT {ECO:0000259|PROSITE:PS51507}.
SQ SEQUENCE 460 AA; 52332 MW; B0EA21D8D9DAA143 CRC64;
MALQPRRVRL KPWLVAQVDS GMYPGLIWLN REAKRFQIPW KHATRHSPQQ EEENTIFKAW
AVETSKYQEG ADEPDPAKWK AQLRCALNKS REFKLMYDGT KEVPMNPVKI YEVCDIPQSQ
GSIINPGSAG SAPWDDDDFE ESELNKSQNH VPIQEPFNCL NISADSPMGS TSTGSCTPEQ
TWPKTEPQEM EVPPAAGPAD FFSSPEMWIS SLPMTDLEIQ FYYRGKEMGQ ATTVSNPQGC
RLFYGDLGPM PNQEELFGPI TLEQVRFPGT EQIVNEKQKL FTSRLLDVMD RGLILEVSGH
AIYAIRLCQC KVYWNGPCSP SQTTPNLIER QKRVKLFCLE TFLSELISHQ KGVVTKQPPY
EIYLCFGEEW PDGKSKERKL IIVQIIPIVA RMILEMFSGD STRSFDSGSI RLQISVPDIK
DNIVAHLKQL YRLLQNHQGP DAWPLMQPQN MHLAQTLQAQ
//
