ID Q28HT0_XENTR Unreviewed; 696 AA.
AC Q28HT0; A0A6I8QQ33;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Novel protein similar to staufen {ECO:0000313|EMBL:CAJ83112.1};
DE SubName: Full=Staufen double-stranded RNA binding protein 1 {ECO:0000313|Ensembl:ENSXETP00000070535};
GN Name=stau1 {ECO:0000313|Ensembl:ENSXETP00000070535};
GN ORFNames=TTpA004b17.1-001 {ECO:0000313|EMBL:CAJ83112.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:CAJ83112.1};
RN [1] {ECO:0000313|EMBL:CAJ83112.1}
RP NUCLEOTIDE SEQUENCE.
RA Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
RA Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
RA McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G., Voigt J.,
RA Zorn A.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSXETP00000070535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000070535};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [3] {ECO:0000313|Ensembl:ENSXETP00000070535}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; CR760757; CAJ83112.1; -; mRNA.
DR RefSeq; NP_001016542.2; NM_001016542.2.
DR DNASU; 549296; -.
DR Ensembl; ENSXETT00000101881; ENSXETP00000070535; ENSXETG00000001783.
DR GeneID; 549296; -.
DR KEGG; xtr:549296; -.
DR AGR; Xenbase:XB-GENE-920408; -.
DR CTD; 6780; -.
DR Xenbase; XB-GENE-920408; stau1.
DR OrthoDB; 2882160at2759; -.
DR Bgee; ENSXETG00000001783; Expressed in brain and 15 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19879; DSRM_STAU1_rpt1; 1.
DR CDD; cd19881; DSRM_STAU1_rpt2; 1.
DR CDD; cd19883; DSRM_STAU1_rpt3; 1.
DR CDD; cd19885; DSRM_STAU1_rpt4; 1.
DR CDD; cd19887; DSRM_STAU1_rpt5; 1.
DR Gene3D; 3.30.160.20; -; 5.
DR Gene3D; 6.10.250.1360; -; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR044475; STAU1_DSRM_3.
DR InterPro; IPR032478; Staufen_C.
DR PANTHER; PTHR46054:SF2; DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 1; 1.
DR PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR Pfam; PF00035; dsrm; 3.
DR Pfam; PF16482; Staufen_C; 1.
DR SMART; SM00358; DSRM; 4.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 4.
DR PROSITE; PS50137; DS_RBD; 4.
PE 2: Evidence at transcript level;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 81..148
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 167..257
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 279..346
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 381..449
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 654..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..696
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 76126 MW; DB3B77D5D30A5FE7 CRC64;
MDVNMSQVPN SPAATLSGSQ ILNKNQHSPL PQPLSIPSTA SPLPSENAGR PLQNSALPSP
SVTSSSPAAV SSNMANPKEK TPMCLVNELA RFNKIQPVYK LLSEQGPAHS KMFTVQLTLG
DQYWEAEGTS IKKAQHAAAA KALEGTKYPK PTVRPVRGER KYPDSITPTV ELNALCMKLG
RKPTYKPLDP YTGIRSAYNY NMRGGGYPPR YFYPFPVAPI LYQVELSIGG QQFHGKGRTR
QAAKHDAAAK ALKSLQHEPL PDKPAVNGKA ADEENLNKSE ISQVFEIALK RNMSVNFEVT
KETGPPHMKS FVTKVIVGEF LGEGEGKSKK ISKKNAAISV LEELRKLPPL PTVEKMKPKI
KKKTKSIVKL PTSPEYGQGM NPISRLAQIQ QAKKDKEPEY ILITERGLPR RREFVMQVKV
GNHSAEGMGT NKKVAKRNAA ENMLELLGFK VPPPPPKPAL KTEEKLPLKK PGDGRKVTFY
EPGSGEDTSN NNKDDEFRMP FHSHQQLPAG ILPMVPEVAQ AVGVNQGLHT KEFNRVAPNP
AKATVTAMIA RELLYAGISP TADTILKNNN NAAGLVLHGP FTRPSEQLNY LSRVQGVEVE
YKDFPKNNKN EFVSLINCSS QPPLISHGIG KDVESCHDMA ALNILKLLSE LDQQNPEMPR
TGNGPMSVCV KPEMESDPLL KPANSNTLGQ TLDSTA
//
