ID Q28IL1_XENTR Unreviewed; 395 AA.
AC Q28IL1;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Very low density lipoprotein receptor {ECO:0000313|EMBL:CAJ82714.1};
DE Flags: Fragment;
GN Name=vldlr {ECO:0000313|EMBL:CAJ82714.1};
GN ORFNames=TNeu056a15.1-001 {ECO:0000313|EMBL:CAJ82714.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:CAJ82714.1};
RN [1] {ECO:0000313|EMBL:CAJ82714.1}
RP NUCLEOTIDE SEQUENCE.
RA Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
RA Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
RA McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G., Voigt J.,
RA Zorn A.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR760336; CAJ82714.1; -; mRNA.
DR AlphaFoldDB; Q28IL1; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00112; LDLa; 4.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 5.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24270:SF8; VERY LOW-DENSITY LIPOPROTEIN RECEPTOR; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF00057; Ldl_recept_a; 5.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00192; LDLa; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57424; LDL receptor-like module; 5.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01209; LDLRA_1; 3.
DR PROSITE; PS50068; LDLRA_2; 5.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Lipoprotein {ECO:0000313|EMBL:CAJ82714.1};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:CAJ82714.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 330..365
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 104..116
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 111..129
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 123..138
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 143..155
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 150..168
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 162..177
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 182..194
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 189..207
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 212..224
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 219..237
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 231..246
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 260..278
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 334..344
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAJ82714.1"
FT NON_TER 395
FT /evidence="ECO:0000313|EMBL:CAJ82714.1"
SQ SEQUENCE 395 AA; 42861 MW; 36260FCEB206DB16 CRC64;
GPASSTPLLP GIVHAIQTPP PPRLLAGTLW IFFKGSRQGV LYNVGRSRAA SVPVCIIPSD
RISGGLGAAG CSEMSRSWRG VVLLLLLCCL HPDLGLVHAT KTLCEGSQFQ CANGHCITSL
WKCDGESDCP NAEDEENCGN ITCSPAEFTC SSGRCISSTF VCNGQNDCSD GSDEENCVPP
TCGAHEFQCK NSSCIPLNWV CDDEMNCPSR TCQPDQFKCE DGNCIHGSRQ CDGVRDCLDG
TDEIRCKNVN QCSGPGKFKC RSGECIDIAK VCNKQKDCKD WSDEPIKECY VNECEVNNGG
CSHLCHNLVI GYECDCTAGF KLIDRKTCGD IDECQNPEIC SQICVNLKGG YKCECSKGYQ
MDPSTGVCKA VGREPCLIFT NRRDIRKVGL ERNFL
//
