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Database: UniProt
Entry: Q2BQG1_NEPCE
LinkDB: Q2BQG1_NEPCE
Original site: Q2BQG1_NEPCE 
ID   Q2BQG1_NEPCE            Unreviewed;       543 AA.
AC   Q2BQG1;
DT   04-APR-2006, integrated into UniProtKB/TrEMBL.
DT   04-APR-2006, sequence version 1.
DT   05-JUL-2017, entry version 72.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=MED92_05613 {ECO:0000313|EMBL:EAR62570.1};
OS   Neptuniibacter caesariensis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Neptuniibacter.
OX   NCBI_TaxID=207954 {ECO:0000313|EMBL:EAR62570.1, ECO:0000313|Proteomes:UP000002171};
RN   [1] {ECO:0000313|EMBL:EAR62570.1, ECO:0000313|Proteomes:UP000002171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MED92 {ECO:0000313|EMBL:EAR62570.1,
RC   ECO:0000313|Proteomes:UP000002171};
RA   Pinhassi J., Pedros-Alio C., Ferriera S., Johnson J., Kravitz S.,
RA   Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H.,
RA   Friedman R., Venter J.C.;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAR62570.1}.
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DR   EMBL; AAOW01000002; EAR62570.1; -; Genomic_DNA.
DR   RefSeq; WP_007021588.1; NZ_CH724126.1.
DR   ProteinModelPortal; Q2BQG1; -.
DR   STRING; 207954.MED92_05613; -.
DR   EnsemblBacteria; EAR62570; EAR62570; MED92_05613.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   OMA; DFRYLQG; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002171; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002171};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002171}.
FT   DOMAIN      240    445       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      451    520       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     248    255       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   543 AA;  60675 MW;  2E6208660A4C22EC CRC64;
     MSTELWARCL HSLQDEFPAQ QYNTWIRPLQ VSPDSADQLV LVAPNRFVRD WVNDKFLSRI
     RQVVCDVTGD ISTEVALEVA NNRGMAPRPR PAAASYARRP APAPVSQPAF APAPAVEPVP
     VNEPASVAAA APAQTIITPE TLREESYQQP VAQQIVTPTQ ESIPSQIQMP MHMPPSDIIP
     TPPPAPMPEP IERTVNVEGS LRTHQSNLNQ SFTFESFVQG KSNQLALAAA RQVGDNPGVS
     YNPLFIYGGV GLGKTHLMHA VGNEMLKRNP NAKIVYLHSE RFVADMVKAL QLNAINDFKR
     YYRSVDALLI DDIQFFAGKE RSQEEFFHTF NALLEGGQQM ILTSDRYPKE INGVEERLKS
     RFGWGLTVAI EPPELETRVA ILMKKADEAR VRLPDDAAFF LAQKIRSNVR ELEGALKRVI
     ANAHFTGSAI TTPFIKESLK DLLALQDKQV SIDNIQRVVA DYYKIKVSDL LSKRRSRSVA
     RPRQVAMSLS KELTNHSLPE IGNAFGGRDH TTVLHACRKI KELRESDTDI REDYQNLLRH
     LTA
//
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