ID Q2C8B9_9GAMM Unreviewed; 316 AA.
AC Q2C8B9;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Magnesium transport protein CorA {ECO:0000256|ARBA:ARBA00019439, ECO:0000256|RuleBase:RU362010};
GN Name=corA {ECO:0000256|RuleBase:RU362010};
GN ORFNames=SKA34_06395 {ECO:0000313|EMBL:EAR57365.1};
OS Photobacterium sp. SKA34.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=121723 {ECO:0000313|EMBL:EAR57365.1, ECO:0000313|Proteomes:UP000005284};
RN [1] {ECO:0000313|EMBL:EAR57365.1, ECO:0000313|Proteomes:UP000005284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SKA34 {ECO:0000313|EMBL:EAR57365.1,
RC ECO:0000313|Proteomes:UP000005284};
RA Hagstrom A.J., Ferriera S., Johnson J., Kravitz S., Halpern A.,
RA Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates influx of magnesium ions.
CC {ECO:0000256|RuleBase:RU362010}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Mg(2+)(in) = Mg(2+)(out); Xref=Rhea:RHEA:29827,
CC ChEBI:CHEBI:18420; Evidence={ECO:0000256|ARBA:ARBA00034269};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362010}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR57365.1}.
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DR EMBL; AAOU01000002; EAR57365.1; -; Genomic_DNA.
DR RefSeq; WP_006644236.1; NZ_CH724141.1.
DR AlphaFoldDB; Q2C8B9; -.
DR HOGENOM; CLU_007127_5_0_6; -.
DR OrthoDB; 9803416at2; -.
DR Proteomes; UP000005284; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd12835; EcCorA-like_1; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR NCBIfam; TIGR00383; corA; 1.
DR PANTHER; PTHR47685; MAGNESIUM TRANSPORT PROTEIN CORA; 1.
DR PANTHER; PTHR47685:SF1; MAGNESIUM TRANSPORT PROTEIN CORA; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU362010};
KW Ion transport {ECO:0000256|RuleBase:RU362010};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|RuleBase:RU362010};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362010};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT TRANSMEM 255..278
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362010"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362010"
SQ SEQUENCE 316 AA; 36568 MW; B3687EAEB4216212 CRC64;
MLNAFKLNDS RLQRLDLEAQ APISSALWVD LIEPNEEERV RVQLELGQEL ATRPELEDIE
ASARFFEDED GLHIHSFFYY EDAEDYANNS TVAFTIRDGR LFTLRERELP AFRLYRMRAR
TQHLQQGNAY ELLLDLFETK IEQLADVIED IYSALESIGK IILGGKPGEH FDKALSNLAE
QEDAGWKIRL CLMDTQRALS FLVRKARLPA NELEQAREVL RDIESLLPHN ESLFQKVNFL
MDAAMGFINI EQNRIIKIFS VVSVVFLPPT LVASSYGMNF EFMPELHWKL GYPYALLLMV
LAALAPYLYF KRKGWL
//
