ID Q2ETU5_SHIFL Unreviewed; 265 AA.
AC Q2ETU5;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=NikC {ECO:0000313|EMBL:ABD20243.1};
DE Flags: Fragment;
GN Name=nikC {ECO:0000313|EMBL:ABD20243.1};
OS Shigella flexneri.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623 {ECO:0000313|EMBL:ABD20243.1};
RN [1] {ECO:0000313|EMBL:ABD20243.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=581 {ECO:0000313|EMBL:ABD20243.1};
RX PubMed=17160643; DOI=10.1007/s00239-006-0052-8;
RA Yang J., Nie H., Chen L., Zhang X., Yang F., Xu X., Zhu Y., Yu J., Jin Q.;
RT "Revisiting the molecular evolutionary history of Shigella spp.";
RL J. Mol. Evol. 64:71-79(2007).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
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DR EMBL; DQ362584; ABD20243.1; -; Genomic_DNA.
DR AlphaFoldDB; Q2ETU5; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015099; F:nickel cation transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR014157; Nickel_NikC.
DR NCBIfam; TIGR02790; nickel_nikC; 1.
DR PANTHER; PTHR43386:SF14; NICKEL TRANSPORT SYSTEM PERMEASE PROTEIN NIKC; 1.
DR PANTHER; PTHR43386; OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN APPC; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032}; Transport {ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 115..142
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 171..190
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 197..216
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 61..254
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABD20243.1"
FT NON_TER 265
FT /evidence="ECO:0000313|EMBL:ABD20243.1"
SQ SEQUENCE 265 AA; 28890 MW; C6A523692E462839 CRC64;
SRWSVRLALI IIALLALIAL TSQWWQPYDP QAIDLPSCLL SPDAQHWLGT DHLGRDIFSR
LMAATRVSLG SVMACLLLVL TLGLVIGGSA GLIGGHVDQA TMRVADMFMT FPTSILSFFM
VGVLGTGLTN VIIAIALSHW AWYARMVRSL VISLRQREFV LASRLSGAGH VRVFVDHLAG
AVIPSLLVLA TLDIGHMMLH VAGMSFLGLG VTAPTAEWGV MINDARQYIW TQPLQMFWPG
LALFISVMAF NLVGDALRDH LDPHL
//
