ID Q2FNC1_METHJ Unreviewed; 209 AA.
AC Q2FNC1;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=NADPH-dependent FMN reductase {ECO:0000313|EMBL:ABD42427.1};
GN OrderedLocusNames=Mhun_2732 {ECO:0000313|EMBL:ABD42427.1};
OS Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS JF-1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD42427.1, ECO:0000313|Proteomes:UP000001941};
RN [1] {ECO:0000313|Proteomes:UP000001941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC {ECO:0000313|Proteomes:UP000001941};
RX PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL Stand. Genomic Sci. 11:2-2(2016).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the SsuE family. Isf subfamily.
CC {ECO:0000256|ARBA:ARBA00038292}.
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DR EMBL; CP000254; ABD42427.1; -; Genomic_DNA.
DR RefSeq; WP_011449683.1; NC_007796.1.
DR AlphaFoldDB; Q2FNC1; -.
DR STRING; 323259.Mhun_2732; -.
DR EnsemblBacteria; ABD42427; ABD42427; Mhun_2732.
DR GeneID; 3922205; -.
DR KEGG; mhu:Mhun_2732; -.
DR eggNOG; arCOG02572; Archaea.
DR HOGENOM; CLU_050993_4_1_2; -.
DR InParanoid; Q2FNC1; -.
DR OrthoDB; 9059at2157; -.
DR Proteomes; UP000001941; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.40.50.360; -; 1.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR005025; FMN_Rdtase-like.
DR PANTHER; PTHR43278:SF1; IRON-SULFUR FLAVOPROTEIN MJ1083; 1.
DR PANTHER; PTHR43278; NAD(P)H-DEPENDENT FMN-CONTAINING OXIDOREDUCTASE YWQN-RELATED; 1.
DR Pfam; PF03358; FMN_red; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000001941}.
FT DOMAIN 6..106
FT /note="NADPH-dependent FMN reductase-like"
FT /evidence="ECO:0000259|Pfam:PF03358"
SQ SEQUENCE 209 AA; 22827 MW; 868742CC7574D907 CRC64;
MKKTVTVIGL SGSPRRRGNT EQLLDRFLAG ASDAGGITEK VVLSTLEYSS CKGCNACHQT
GTCIMDDAVR ELYDRMLAAD CIIISSPIYT MGITAELKSF IDRAHYIWVR HFVLGSHIIS
PEEKKLRRGY FLSTAGMDQA DVFDTAYPMI RALFNILGFT HCAGYLASNM DGYGGITGHP
TALDDVYRIG TSAVTGIMAG RPCLELARR
//
