ID Q2FS16_METHJ Unreviewed; 281 AA.
AC Q2FS16;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Thiamine pyrophosphate enzyme-like TPP-binding protein {ECO:0000313|EMBL:ABD42680.1};
GN OrderedLocusNames=Mhun_2993 {ECO:0000313|EMBL:ABD42680.1};
OS Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS JF-1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD42680.1, ECO:0000313|Proteomes:UP000001941};
RN [1] {ECO:0000313|Proteomes:UP000001941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC {ECO:0000313|Proteomes:UP000001941};
RX PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL Stand. Genomic Sci. 11:2-2(2016).
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DR EMBL; CP000254; ABD42680.1; -; Genomic_DNA.
DR RefSeq; WP_011449933.1; NC_007796.1.
DR AlphaFoldDB; Q2FS16; -.
DR STRING; 323259.Mhun_2993; -.
DR EnsemblBacteria; ABD42680; ABD42680; Mhun_2993.
DR GeneID; 3922908; -.
DR KEGG; mhu:Mhun_2993; -.
DR eggNOG; arCOG01599; Archaea.
DR HOGENOM; CLU_048564_0_0_2; -.
DR InParanoid; Q2FS16; -.
DR OrthoDB; 30755at2157; -.
DR Proteomes; UP000001941; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd03375; TPP_OGFOR; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001941}.
FT DOMAIN 51..198
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 281 AA; 31443 MW; 505320C5B6A51043 CRC64;
MSPNATLVSE AKNTWCPGCG NFAIQHAFRY VIEEYEKEGI PKEKFVLVSG IGCHAKIVDY
FNLNSFYSLH GRTIPVATGI KMANPDLKVV CFAGDGDLYA EGLDHLIHAA KRNIDITVIC
HNNRVYGLTT GQYTPTSPYG YQGRSTPNGI HEYPLNIIEV LLGSGAGFVA RAYSRNIPLL
KRVIHEAISH PGFAHIDVLQ ICATFFNMTS VYDEQVYETS EANVSQFDMA CRTGQQWNYS
DPGPIPLGIF YKTIRPSLPE KREIKQTDRK KVIQEILSRY S
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