ID Q2G3V9_NOVAD Unreviewed; 484 AA.
AC Q2G3V9;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Radical SAM {ECO:0000313|EMBL:ABD27464.1};
GN OrderedLocusNames=Saro_3029 {ECO:0000313|EMBL:ABD27464.1};
OS Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG
OS 56034 / CIP 105152 / NBRC 16084 / F199).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=279238 {ECO:0000313|EMBL:ABD27464.1, ECO:0000313|Proteomes:UP000009134};
RN [1] {ECO:0000313|Proteomes:UP000009134}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084
RC / F199 {ECO:0000313|Proteomes:UP000009134};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N.,
RA Fredrickson J., Balkwill D., Romine M.F., Richardson P.;
RT "Complete sequence of Novosphingobium aromaticivorans DSM 12444.";
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
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DR EMBL; CP000248; ABD27464.1; -; Genomic_DNA.
DR RefSeq; WP_011446668.1; NC_007794.1.
DR AlphaFoldDB; Q2G3V9; -.
DR STRING; 279238.Saro_3029; -.
DR KEGG; nar:Saro_3029; -.
DR eggNOG; COG0641; Bacteria.
DR HOGENOM; CLU_009273_3_3_5; -.
DR Proteomes; UP000009134; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR023886; QH-AmDH_gsu_maturation.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR03906; quino_hemo_SAM; 1.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF8; RADICAL SAM PROTEIN-RELATED; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01216; thioether_bond_formation_requi; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009134};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 102..342
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 484 AA; 52702 MW; EEDA0CD86B04F7CA CRC64;
MTTVLAPRYR LGDIHTFEAS GQGFVYLASA GAIFALDEGA ASVVAMLGQR EMAYGEMVSA
LVANGYSRAD AEDLIRELRS VRGIVSDEIR EAPLAPAPPP EDYPLQALVL NITNQCNLAC
TYCYEFGADK IATPAGKPKY MTLETARASV DFLIAGSGHR EVPHITFFGG ETLMNFKLLR
EVVEYANGAA AAAGKQITYS LTTNATLLTD EIIAFLSDNA VGVTVSMDGP PDLQDKHRVY
KTGKGSYAVI EPRLRKLIAG HRTRAVTARV TLTNGVTDVV RIYRHLKDDL GFHEVGFAPV
TNSGERDYMI DDNGMDHVIA QFHELAAEWL AWALEGRMHG FSNVSETIAE LIQGTNKSHP
CGAGLGLLGV SPSGDLSPCH RFTDSDTHVL GHISTGLDKD KRSDFLTRGH VGAKYECASC
WARPLCAGGC HHEAFVRYGD TGHANLHYCD WIREWTDACL RIYGTVAARN PEFLERFATR
KGLA
//
